摘要
目的:分析原发性喉恶性纤维组织细胞瘤的起源、病理、临床特点及治疗。方法:我院自1990年8月至2000年12月收治4例原发性喉恶性纤维组织细胞瘤患者,均有病理证实,中位年龄为66岁;主要症状是声嘶,呼吸困难,吞咽疼痛。4例均手术治疗,2例行第2次手术治疗(全喉切除术)。3例行术后放疗,采用60Co,6MVX线,放疗剂量为60～62Gy/6周。结果:3例健在,分别已生存11年,4年,3年;1例未放疗者术后复发,颈淋巴结转移,带瘤生存10个月。结论:喉恶性纤维组织细胞瘤具有高度浸润性,易复发,手术加放疗是一种积极有效的措施。
Objective:To analysi s the origin,pathology,clinical characteristics and treatment of patients with Primary malignant fibrous histiocytoma (MFH)of the larynx.Methods:From au-gust1990to December2000,4patients with primary MFH of the larynx were treated in our hospital.All patients were confirmed by histopathology.All wer e men.The median age was66years.The most common symptom was hoarseness,dysp nea,odynophagia.All patients were treated with surgery,2patients were treate d with second surgery (total laryngectomy).3patients were treated with posto perative irradiation with60Co,6MV-X rays.A total dose of60～62Gy in6 weeks was delivered.Results:3patients are alive and well11years,4years an d3years re-spectively,with no evidence of disease.1patient without postop erative irradiation recur and cervi-cal lymph node metastases,is alive10mon ths.Conclusion:Laryngeal MFH has an aggressive biological behaviour.Surgery c ombined with radiotherapy is an effective method.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2003年第6期401-402,412,共3页
Chinese Journal of Clinical Oncology
关键词
喉
恶性纤维组织细胞瘤
治疗
Larynx Malignant f ibrous histiocytoma Therapy
