摘要
目的 探讨影响产超广谱 β 内酰胺酶 (ESBLs)细菌尘肺肺部感染的危险因素 ,预防医院感染暴发。方法 对 2 0 0 2年 7月至 2 0 0 3年 8月间医院发生的 3 5例由产ESBLs肺炎克雷伯菌和大肠埃希菌所致尘肺肺部感染病例、3 0例对照病例的危险因素进行研究。结果 产ESBLs肺炎克雷伯菌和大肠埃希菌引发尘肺肺部感染占 53 85%。发生医院感染的危险因素为联合应用抗生素、病程≥ 15d、入住ICU、应用第三代头孢菌素和喹诺酮类、机械通气。结论 严密监测产ESBLs菌株的感染 ,缩短住院时间 ,控制第三代头孢菌素和喹诺酮类药物的使用 。
Objective To study the risk f ac tors of pneumoconiosis complicated with hospital infection induced by extend sp ectrum β lactamase(ESBLs) producing strains and to prevent its outbreak.Methods Thirty five cases of pneumoconiosis complicated with hospit al infection with ESBLs producing klebsiella pneumonieae and escherichia coli a nd 30 control cases of negative ESBLs strains were studied from July,2002 to Au gust, 2003.Results The percentage infection induced by ESBLs p roducing strains was 53.85%.The risk factors for hospital infection by ESBLs pr oducing strains consisted of combined application of antibiotics,disease course over fifteen days,ICU,use of third generation of cephalosporins and quinolones,v entilation.Conclusion The surveillance for the infection by ESB Ls producing strains,shortened hospitalization days,reasonably using third gene ration of cephalosporins and quinolones,disinfecting the environments should be taken so as to reduce the incidence of the infection.
出处
《中国基层医药》
CAS
2004年第1期25-26,共2页
Chinese Journal of Primary Medicine and Pharmacy
