摘要
目的:探讨儿童先天缺牙的临床特点。方法:常规口腔检查,全口曲面断层X线片,实验室检查和系谱分析。结果:3例患儿的缺失牙齿包括切牙、尖牙、前磨牙及磨牙,数目分别为22,17,17个不等;染色体、微量元素和碱性磷酸酶(ALP)检测结果无明显差异;发病形式有2例为散发,有1例表现为家族性的,后者的遗传方式为Y连锁遗传或常染色体显性遗传。结论:综合征和非综合征性的多数牙先天缺失患者其家系遗传背景和缺牙的位置、数目不同,但实验室检测无明显异常。
AIM:To investigate the clinical characteristics of congenital absence of teeth in children. METHODS:The routine oral examination,panoramic radiograph,laboratory examinati on and pedigree analysis were carried out in 3 children. RESULTS:The absent teeth of the 3 children included incisors,canines as well a s premolars and molars,and the number was 22,17 and 17 respectively.There were n o significant differences in chromosome shape,microelement,and alkaline phosphat ase(ALP).The episode patterns of two cases were sporadic and 1 case were familia l;the latter was autosomal dominant inheritance or Y-linked inheritance. CONCLUSION:The affected patients with syndromic or non-syndromic congenital a bsence of teeth have different genetic background,position and amount of missing teeth,but there are no significant abnormality by laboratory examination.
出处
《中国临床康复》
CSCD
2004年第11期2051-2053,共3页
Chinese Journal of Clinical Rehabilitation
