摘要
本文对348例胃平滑肌肿瘤进行临床病理总结,140例术后获5~28年随访。统计学分析结果表明:患者的年龄、性别、症状体征和肿瘤部位,与预后无明显关系(P>00.5);病程、肿瘤体积、瘤细胞密度、瘤细胞异型、核分裂相计数、瘤细胞坏死和肿瘤生长方式,皆与预后关系密切(P<0.05或P<0.001),但其在每个病例的表现并不完全一致。综合镜下改变的组织学分级,能反映预后的差别。作者建议,0级为良性,Ⅰ级低度恶性,Ⅱ级中度恶性,Ⅲ级高度恶性。分级模棱两可时,若肿瘤直径>10cm,应归入较高级。
Three hundred and forty-eight cases of gastric smooth muscle tumors collected from 16 hospitals in China were analysed.There were 196 males and 152 females.The age of the patients ranged from 1.5 to 82 years. There was no statistical significance of factors such asage,sex,symptoms,location of the tumor in terms of prognosis (P>0.05).But the duration of the disease,size of tumor,compactness of tumor cells,degree of anaplasia of the tumor cell,mitotic figures,tumor coagulation necrosis and growth paftern of the tumor were closely related to the prognosis (P<0.05 or P<0.001) although the impact of different factors varied with different cases. In light of the above parameters which govern the prognosis,the authors suggest a new grading system wherein grade 0 means benign,grade I stands for low malignancy,grade Ⅱ represents middle malignancy,grade Ⅲ high malignancy.When the grading is equivocal and the tumor is more than 10cm in diameter it is justifiable to classify to higher grade.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1992年第2期94-96,共3页
Chinese Journal of Clinical Oncology
关键词
胃
平滑肌肿瘤
组织病理学
预后
Stomach
Smooth muscle tumors
Prognosis
Clinico-pathologic analysis