摘要
目的 :进一步探讨羊水栓塞 (AFE)的临床早期确诊。方法 :前瞻性地对 5例临床拟诊AFE者 ,取中心静脉血或外周血涂片 ,H E滴染 ;取同期 2 2例无心肺功能改变的足月孕妇及同期 4例死亡孕妇作对照组。结果 :5例拟诊羊水栓塞者 ,从作出临床诊断至发病的时间为 4～ 9小时 ,5例细胞学检查均找到角化与不全角化上皮细胞 ;对照组 2 2例孕妇中除 1例HELLP综合征的外周血涂片偶见角化上皮细胞外 ,余 2 1例及 4例死亡孕妇血中均未找到角化或不全角化上皮细胞。结论 :前瞻性地对有典型临床表现或疑诊AFE者进行细胞学检查是一种简单、迅速。
Objective : To investigate the value of cytologic analysis in maternal blood for patients with clinically suspected as Amniotic fluid embolism (AFE). Methods: Five cases, suspected as AFE according to the specific clinical features, were studied prospectively using cytologic analysis to detecting amniotic cells in central or peripheral venous blood. During the same period, 22 normal full-term pregnant women without cardiopulmonary diseases and 4 gravida that died from other causes were recruited as control group. Results: Among five women that suspected AFE, three were survival and two died. There were two stillbirths .The clinical diagnosis of AFE made from the onset of pulmonary symptoms was four to nine hours. Amniotic cells were found in all 5 cases of AFE. There was no amniotic cell be found in control group, except one case with HELLP syndrome. The blood slide was examined routinely with dropped hematoxylin-erosin (H-E) in one dead case suspected as AFE, in which the squamous cell was not found in central venous blood, while the dead cause was confirmed as bleeding in broad ligament by autopsy. Conclusions: The cytologic analysis method is a simple, rapid, and reliable method for early confirming AFE in clinically suspected or typical of AFE.
出处
《实用妇产科杂志》
CAS
CSCD
北大核心
2004年第2期104-106,共3页
Journal of Practical Obstetrics and Gynecology
