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富氧对高原移居者睡眠结构的影响 被引量:23

Effects of oxygen enrichment of room air on sleep patterns at high altitude
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摘要 目的 分析高原移居者在富氧室前后睡眠结构的变化 ,初步评估富氧室对高原移居者睡眠质量的改善作用。方法 在海拔 370 0m建立富氧室 ,12例移居高原 30d的健康青年入室休息和睡眠 10h ,应用上海海神医疗电子仪器厂生产的CFM 8型便携式脑电监测仪进行睡眠监测 ,观察受试者睡眠结构的改变 ,并与常氧组比较。结果 富氧组慢波睡眠比率显著增加 [(19 33± 4 85 ) % ,(13 6 7± 3 75 ) % ,P <0 0 1],总睡眠时间延长 [(5 0 0 83± 32 94 )min ,(470 6 7± 2 7 4 3)min ,P <0 0 5 ],有效睡眠指数明显升高 [(90 33± 2 0 6 ) % ,(85 5 0± 3 34) % ,P <0 0 0 1]。结论 在高原建立富氧室能明显改善移居者的睡眠质量。 Objective To explore how hypoxia circumstance affects sleep architecture and to study the potential use of oxygen enrichment of room air at an altitude of 3700 m. Methods Oxygen concentration was raised to (24.30±0.88)% in a room with a dimension of 4.51 m×3.32 m×3.41 m. Twelve men aged 18 to 20 years who had stayed at high altitude (3700 m above sea level) for 30 days slept one night in a room of ambient air and another night in the oxygen enriched room the order being randomized. Their electroencephalograms (EEG) were recorded with CFM-8 polysomnography. Results Significantly more time was spent in deep sleep (stages Ⅲ and Ⅳ combined,also known as slow-wave sleep) with oxygen enriched than ambient air [(19.33±4.85)% vs (13.67±3.75)%,P <0.01 with paired comparisons]. The total sleep time [(500.83±32.94) min vs (470.67±27.43) min,P <0.05] and the efficient sleep index [(90.33±2.06)% vs (85.50±3.34)%,P <0.001] were increased in oxygen enriched air. No differences between ambient and oxygen enriched air were found in sleep latency the time to fall asleep,the number of arousal and sleep shift (the time spent awake after falling asleep),but there was a trend toward fewer of these with oxygen treatment. Conclusions Installing an oxygen-enriched room at high altitude is relatively simple and inexpensive,and there will be a promise for improving sleep quality,well-being,and work capacity.
机构地区 解放军第
出处 《中华内科杂志》 CAS CSCD 北大核心 2004年第5期368-370,共3页 Chinese Journal of Internal Medicine
基金 全军医药卫生科研基金资助项目 (0 1L0 62 )
关键词 富氧 高原移居者 睡眠结构 睡眠医学 Altitude Dyssomnias Hypoxia,brain
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