摘要
本文观察了大蒜提取物对实验性动脉粥样硬化家兔血小板功能的影响。结果表明;动脉粥样硬化时,血小板粘附和聚集,5-羟色胺(5-HT)释放和血栓烷A_2(TXA_2)生成都增加。给予大蒜提取物,可抑制这些血小板功能亢进现象。提示:大蒜提取物对血小板的影响有利于预防动脉粥样硬化形成。
Effects of garlic extradt on platelets were studied in experimenal atherosclerosis of rabbits. Enhanced platelet aggregation and adhesion, serotonin (5-HT) secretion and thromboxan A2 (TXA_2)production were found in the process oE atherosclerosis. These enhanced platelet activities, however, would be inhibited by the garlic extract (equal to fresh garlic lg/kg weight) given daily throughout the experiment. I0t is concluded that the garlic extract is favorable in prevention of athetosclerosis.
出处
《中国医科大学学报》
CAS
CSCD
1992年第6期436-439,共4页
Journal of China Medical University
关键词
动脉粥样硬化
血小板
大蒜
atherosclerosis
platelet adhesion
platelet aggreation
serotonin) TXA_2 production
garlic extract
