摘要
用酰胺类化合物和气相色谱固定液制备了一种新型固相微萃取膜 ,对膜的性质、吸附解吸条件进行了研究 ;应用该类固相微萃取膜成功地分离了尿液中的吗啡、苯巴比妥以及血液中的敌敌畏 ,并利用气相色谱 -质谱联用技术对分离后的样品进行了分析。
Solid phase micro-extraction membrane(SPMEM) is a new, simple and solventless sample preparation technique which intergrates sampling, extraction and concentration into a single step. It has the advantages of both the solid phase micro-extraction(SPME) and membrane separation. In this paper, a new kind of membrane used for SPME was prepared with amide compounds. The extraction conditions such as adsorption time, desorption solvents, desorption methods and time were studied and optimized. The morphine and phenobarbital in the urine, DDVP in the blood were well separated with this SPME membrane, and were examined by GC-MS. All the data were acquired in scan mode except that of morphine which was obtained in a selected ion monitoring(SIM) mode. Ions used for identification were those with m/z 57, 115, 162, 215, 285.
出处
《分析测试学报》
CAS
CSCD
北大核心
2004年第2期66-68,共3页
Journal of Instrumental Analysis
基金
公安部资助项目 (20002224201)
