摘要
目的 :分析慢性肾功能衰竭 (CRF)患者血中甲状旁腺激素 (PTH)和甲状旁腺激素相关蛋白 (PTHrP)水平的变化。方法 :采用放免法测定 92例CRF患者和 30例正常人血清PTH和血浆PTHrP含量 ,并按CRF分期 ,将CRF患者分为四期。结果 :在慢性肾功能衰竭各个阶段 ,血清PTH、血浆PTHrP含量较正常对照组明显升高 (P <0 .0 1 )。结论 :血清PTH含量及血浆PTHrP均可反映慢性肾功能衰竭的程度 ,其含量随肾功能损害的加重而逐渐升高。血清PTH含量及血浆PTHrP反映肾功能损伤基本一致。
Objective: To investigate the relationship between the Parathyroid hormone (PTH) and the Parathyroid hormone related Protein (PTHrP) and TCM syndromes in chronic renal failure. Methods:Radioimmunoassay (RIA) was used to detect serum PTH and plasma PTHrP in 92 CRF patients and 30 heal thypersons (control group). Results:In the different stages of chronic renal failure, the level of serum PTH and plasma PTHrP were higher than those in control group (p<0.01). Conclusions: The level of serum PTH. And plasma PTHrP can serve as a reference index of impairment of renal function, they increase with the development of renal failure. The level of serum PTH and plasma PTHrP are correlated with the extent of insufficiency.
出处
《河北医学》
CAS
2004年第3期231-233,共3页
Hebei Medicine
