摘要
用耗竭/补充/耗竭的设计,以克山病病区低硒粮饲料(含硒6μg/kg)喂养大鼠6周后,观察了补充紫阳高硒玉米(含硒7.241mg/kg)或亚硒酸钠硒(饲料含硒分别为221和223μg/kg)时以及停止补硒后,大鼠组织和血液硒水平以及谷胱甘肽过氧化物酶(GSH-px)活性的变化,评估了紫阳高硒玉米硒的相对生物利用率。结果表明:以血浆、肾、肝和心肌硒含量为指标时,高硒玉米硒的平均相对生物利用率(补硒2、4和6周时)与亚硒酸钠硒相似,分别为99、107、100和104%(亚硒酸钠定为100%);但以红细胞硒为指标时,高硒玉米硒的生物利用率(120%)高于亚硒酸钠硒;以心肌和红细胞 GSH-px 活性为指标时,其生物利用率(72和84%)低于亚硒酸钠硒。至再停止补硒3周时,高硒玉米维持组织硒水平和 GSH-px 活性的作用与亚硒酸钠相似。
A three-phase depletion/repletion/depletion feeding study was (?)to evaluate the relative bioavailability of Se in the Ziyang high-Se cornto rats fed low-Se diet.The results showed that the average bioavailabilityof Se in high-Se corn derived from the values at wk 2,4 and 6 of suplementwas close to that in selenite when estimated by plasma,kidney,liver andheart Se contents,the relative bioavailabilities being 99,107,100 and 104%(sodium selenite=100%) respectively.when erythrocyte Se was the responsecriterion,the bioavailability (120%) was greater than that of in selenite.The bioavailabity was lowr for Se in high-Se corn (72 or 84%) than forselenite when the criterion used was either heart or erythrocyte CSH-px activity.
出处
《中国地方病学杂志》
CAS
CSCD
1992年第4期193-195,共3页
Chinese Jouranl of Endemiology
关键词
玉米
硒
酶
克山病
High-Se corn
sodium selenite
selenium
glutathione peroxidase
bioavailability
Keshan disease
rat