摘要
本文对黄石市橡胶行业1971年1月1日至1973年12月31日在岗1223名工人进行恶性肿瘤回顾性队列研究表明,橡胶恶性肿瘤占死因首位,其全部肿瘤,男、女肿瘤死亡分别为112.03/10万、158.26/10万、62.49/10万,与对照组比较,标准化相对危险度(SRR)分别为2.50、2.62、2.27;与当地人群比较SMR分别为257、208、220,均有统计学意义。RSMR分析提示男性肝癌、胃癌、鼻咽癌,女性白血病、乳腺癌等多个部位肿瘤死亡增加。本研究还提示该行业恶性肿瘤高发可能与亚硝胺类、防老剂D、苯等有害因素的联合作用有关。
A retrospective cohort mortality study was conducted at the rubber plants in Huangshi to investigate the cancer patterns of 1223 workers who had worked between Jan. 1, 1971 and Dec. 31, 1973, and had been followed up to Dec. 31, 1989. The cancer mortality rates of men and women and all were 158.26/100000, 62.49/100000, 112.03/100000 respectively; standardized risk ratio (SRR) were 2.62, 2.27, 2.50 respectively; and standardized mortality ratio (SMR) were 208, 220, 257 respectively. All these figures were significantly higher than that of the control and of local population. It also showed statistically significant excess of deaths of liver, gastric and nasopharyngeal cancer in men and also of breast cancer and leukaemia in women. It suggested that the result were probably caused by the joint action of benzene, nitrosamines and PBNA.
出处
《职业医学》
1992年第3期135-137,共3页
China Occupational Medicine
关键词
橡胶
肿瘤
亚硝胺
防老剂D
苯
rubber,cancer,retrospective cohort study,benzene,nitrosamines,PBNA
