摘要
目的:比较和分析心脏病患病与否的脑血管血流动力学指标(cerebralvascularhemodynamicindes,CVHI)的差异和变化特征。方法:以整群抽样的方法抽取上海市南汇区4个镇35岁以上人群,选择心脏病患者进行CVHI检测并对检测指标进行统一积分,以1∶1的比例在人群中选择无脑卒中危险因素暴露者作为对照组,分析两组人群CVHI检测指标和积分的差异。结果:心脏病组脑血管功能平均积分为(78.11±24.57)分,对照组为(88.92±14.59)分,心脏病组的积分显著低于对照组(P<0.001);心脏病组的平均血流量(Qmean)、平均血流速度(Vmean)、最大血流速度(Vmax)、最小血流速度(Vmin)和临界压与舒张之差(DP)显著低于对照组(P<0.001),而外周阻力(RV)显著高于对照组(P<0.05)。CVHI指标变化幅度较大的分别为DP,Vmin,Qmean,Vmean,Vmax和RV。结论:心脏病患者的CVHI指标变化特征主要表现为血流速度减慢、外周阻力升高和脑血管功能积分降低。
AIM:To compare and analyze the differences and characteristics of cerebral vascular hemodynamic indexes(CVHI) between heart disease patients and normal controls.METHODS:The CVHI indexes were checked in the population aged above 35 years at 4 towns of Nanhui district in Shanghai by sampling in clusters.The heart disease patients in the population were defined as the case group and individuals without exposure of dangerous factors selected from the population as control group at a ratio of 1∶1 matched in age and sex.Differences of CVHI indexes between the two groups were compared.RESULTS:Average integral score of cerebral vascular function in the case group was 78.11±24.57,significantly lower than that in the control group(88.92±14.59)(P< 0.001).The average blood flow(Qmean),average flow velocity(Vmean),maximum flow velocity(Vmax),minimum flow velocity(Vmin) and pressure difference between critical pressure and diastolic pressure(DP) were significantly lower(P< 0.001),and peripheral resistance(Rv) was significantly higher in the case group(P< 0.05),as compared with the control group.The CVHI indexes had great changes in DP,Vmin,Qmean,Vmean and Vmax.CONCLUSION:The main characteristics of CVHI indexes include less blood velocity,increased peripheral resistance and decreased integral scores of cerebral vascular function.
出处
《中国临床康复》
CSCD
2004年第7期1230-1231,共2页
Chinese Journal of Clinical Rehabilitation
基金
上海市科学技术委员会项资助项目(沪科合99第005号)~~
