摘要
目的:探讨采用布托啡诺、舒芬太尼及罗哌卡因硬膜外分娩镇痛对产妇血浆催乳素的影响。方法:回顾性分析2016年3月—2018年9月在我院自然分娩的90例产妇的临床资料,根据是否进行分娩镇痛分为对照组(未进行分娩镇痛,40例)和观察组(实施布托啡诺、舒芬太尼及罗哌卡因硬膜外分娩镇痛,50例),比较两组血浆催乳素浓度、视觉模拟评分法(VAS)评分及分娩结局。结果:观察组产后48 h血浆催乳素浓度均高于对照组,差异有统计学意义(P <0.05);观察组镇痛后30 min及宫口全开时VAS评分低于对照组,差异有统计学意义(P<0.05);两组剖宫产、手术助产及新生儿窒息发生率比较,差异无统计学意义(P>0.05);观察组顺产率高于对照组,差异有统计学意义(P <0.05)。结论:布托啡诺、舒芬太尼及罗哌卡因硬膜外分娩镇痛可减轻产妇疼痛程度,减少对血浆催乳素的影响,提高顺产率。
Objective:To investigate the effect of epidural analgesia during labor with butorphanol,sufentanil and ropivacaine on plasma prolactin in parturients.Methods:The clinical data of 90 parturients who delivered naturally in our hospital from March 2016 to September 2018 were retrospectively analyzed,and the parturients were divided into a control group(40 cases without analgesia)and an observation group(50 cases with epidural analgesia with butorphanol,sufentanil and ropivacaine)according to the analgesia situation during labor.The plasma concentration of prolactin,visual analogue scale(VAS)scores and labor outcomes were compared between the two groups.Results:The plasma concentration of prolactin at 48 h after labor in the observation group was higher than that in the control group,and the difference was statistically signi?cant(P<0.05).The VAS scores at 30 min after analgesia and at the time of full opening of the cervixes in the observation group were lower than those in the control group,and the differences were statistically signi?cant(P<0.05).There were no statistically signi?cant differences in the incidences of cesarean section,surgical midwifery and neonatal asphyxia between the two groups(P>0.05).The spontaneous labor rate in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:Epidural analgesia during labor with butorphanol,sufentanil and ropivacaine can alleviate maternal pain,reduce the effect on plasma prolactin and increase the rate of spontaneous labor.
作者
邓超
Deng Chao(Department of Anesthesiology,Xinyang Hospital of Traditional Chinese Medicine,Xinyang Henan 464000 China)
出处
《中国合理用药探索》
CAS
2019年第5期134-136,共3页
Chinese Journal of Rational Drug Use
