摘要
患者女,61岁。右拇指背侧结节、溃疡3年。皮损组织病理示真皮下部肿瘤细胞团块浸润伴周围坏死,瘤体由上皮样细胞及梭形细胞构成,部分细胞异型性明显。免疫组化染色示肿瘤细胞表达波形蛋白、上皮膜抗原、PCK及CD34,不表达CK5/6及S-100蛋白,Ki-67约20%阳性。头部MRI提示合并脑膜瘤。本病临床少见,其皮损的临床病理特点与感染性肉芽肿类似,应加强对本病的认识,可减少误诊。
A 61-year-old female presented with multiple nodules with ulceration on the dorsum of her right thumb for there years. Histopathological examination showed tumor cells infiltrations in lower dermis with necrosis around. The tumor cells were comprised of epithelioid and spindle cells with mild to moderated atypia. Immunohistochemically,the tumor cells were positively stained for Vimentin,PCK and CD34,but negative for CK5/6 and S-100. The percentage of Ki-67 positively stained cells was about 20%.The head MRI indicated a complication of meningioma.
作者
唐新月
唐教清
王琳
TANG Xinyue;TANG Jiaoqing;WANG Lin(Department of Dermatology,West China Hospital,Sichuan University,Chengdu 610041,China)
出处
《皮肤科学通报》
2019年第1期95-97,共3页
Dermatology Bulletin
关键词
上皮样肉瘤
感染性肉芽肿
误诊
皮肤肿瘤
Epithelioid sarcoma
Infectious granuloma
Misdiagnose
Skin tumors
