摘要
Objective To explore promoter methylation of HIC1gene and the expression of HIC1/SIRT1 related to the occurrence,development,and metastasis of papillary thyroid carcinoma.Methods Using Bisulfite sequencing PCR to analyze the promoter methylation of HIC1 gene.Using quantitative real-time PCR and Western blot to analyze expression differences of HIC1 and SIRT1 genes
