摘要
肠易激综合征是临床常见病多发病,其机制尚未明了。瞬时受体电位香草酸受体1(TRPV1)在肠易激综合征内脏高敏感性发生中起到重要的作用。肠易激综合征中结肠组织等处的TRPV1呈高表达,中医药可以降低TRPV1表达从而达到治疗肠易激综合征的目的。本文以中医药调控TRPV1治疗肠易激综合征为契机来探讨中医药治疗肠易激综合征的优势。
Irritable bowel syndrome is a common clinical disease,its mechanism is not clear.Transient receptor potential vanillic acid receptor 1(TRPV1)plays an important role in visceral hypersensitivity in irritable bowel syndrome.In irritable bowel syndrome,the expression of TRPV1 is high in colon tissue and other places.TCM can reduce the expression of TRPV1 to treat irritable bowel syndrome.This article discusses the advantages of TCM in treating irritable bowel syndrome by regulating TRPV1.
作者
冯文林
伍海涛
FENG Wenlin;WU Haitao(College of Traditional Chinese Medicine,Southern Medical University,Guangzhou510515,China;Institute of Clinical Pharmacology,Guangzhou University of Chinese Medicine,Guangzhou510405,China)
出处
《吉林中医药》
2019年第6期824-826,共3页
Jilin Journal of Chinese Medicine
基金
国家自然科学基金(81303121)
2017年广东省中医药局面上科研项目(20171167)
广东省自然科学基金项目(2018A03013844)
