摘要
目的探讨分析中西医结合治疗糜烂型口腔扁平苔藓(EOLP)的临床疗效,从而为今后中西医结合治疗EOLP提供新依据。方法选取2016年1月至2017年12月我院口腔科收治的100例EOLP患者为研究对象,将其随机分为试验组与对照组,每组均为50例。对照组患者采用常规西医治疗,试验组患者则在对照组的基础上进行中医辨证施治。观察两组患者的临床疗效、治疗前及治疗后1个月、2个月的疼痛评分变化情况以及不良反应发生情况。结果两组患者的临床治疗总有效率比较试验组显著高于对照组[48/50(96.0%)比40/50(80.0%),χ~2=5.328,P <0.05],差异有统计学意义。两组患者治疗前VAS评分比较,差异无统计学意义(P>0.05)。两组患者治疗1周和治疗2周的VAS评分分别与治疗前比较均明显降低,且试验组治疗1周VAS评分[(4.81±0.62)分比(6.61±0.73)分]和治疗2周[(2.66±0.57)分比(3.71±0.42)分]均显著低于对照组,差异均有统计学意义(均P<0.05)。两组患者在治疗过程中均未出现出严重不良反应。结论对EOLP患者采用中西医结合的方式进行治疗,可显著提高患者的临床治疗效果以及降低其疼痛度评分,而且并无严重不良反应发生,值得进行临床推广与应用。
Objective To analyze the clinical efficacy of integrated traditional Chinese and Western medicine in the treatment of erosive oral lichen planus(EOLP),so as to provide a new basis for the future treatment of EOLP with integrated Chinese and Western medicine.Methods One hundred patients with EOLP admitted to our department of stomatology from January 2016 to December 2017 were enrolled in the study.They were randomly divided into the experimental group and the control group,with 50 cases in each group.The patients in the control group were treated with conventional Western medicine,and the patients in the experimental group were treated with TCM syndrome differentiation on the basis of the control group.The clinical efficacy of the two groups of patients,changes in pain scores before and after treatment,and 1 month and 2 months after treatment were observed.Results The total effective rate of clinical treatment was significantly higher in the two groups than in the control group[48/50(96.0%)vs 40/50(80.0%),χ~2=5.328,P <0.05].The difference was statistically significant..There was no significant difference in the VAS scores between the two groups before treatment(P >0.05).The VAS scores of the two groups at 1 week and 2 weeks after treatment were significantly lower than those before treatment,and the VAS score of the test group was 1 week([4.81±0.62)points vs(6.61±0.73)points and 2 weeks of treatment](2.66±0.57)points vs(3.71±0.42)points were significantly lower than the control group,the difference was statistically significant(P <0.05).No serious adverse reactions occurred in the two groups during the treatment.Conclusion The treatment of EOLP patients with integrated Chinese and Western medicine can significantly improve the clinical treatment effect and reduce the pain score,and there is no serious adverse reaction,which is worthy of clinical promotion and application.
出处
《中国误诊学杂志》
CAS
2018年第7期304-306,共3页
Chinese Journal of Misdiagnostics
关键词
中西医结合
糜烂型口腔扁平苔藓
临床疗效
不良反应
integrated traditional Chinese and Western medicine
erosive oral lichen planus
clinical efficacy
adverse reactions
