摘要
目的三维重建功能在临床上已被广泛应用于临床的术前诊断评估,但对于食管肿瘤术前评估的应用研究甚少。本研究旨在探讨三维重建技术在食管下段肿瘤患者术前诊断中的应用,以提高食管癌的诊断和治疗水平,为患者术前评估提供一种更精准、科学的方法。方法所有患者均于2014年1月至2015年8月在吉林大学第一医院接受食管癌治疗。本研究收集患者的影像资料,应用表面重建技术重建食管肿瘤及邻近结构。分析并计算肿瘤的形状和其他具体参数,并对不同条件下的三维重建结果进行比较。研究使用IBM SPSS 19对所有数据进行分析。所有数据均在3次测量中进行平均。采用t检验、方差分析比较组间差异,P<0.05被视为差异有统计学意义。结果本研究共纳入在72例患者,其中48例胃镜能够通过食道病变,24例不能通过。48例患者的病变部位在30cm-42cm之间。内镜测量长度和三维长度均大于病理长度(P<0.05),但内镜测量长度与三维长度无显著性差异。在CT阳性淋巴结重建数据中,阴性组淋巴结的长度、直径、体积、CT值和重建与阳性组比较有显著性差异。结论三维重建在食管癌术前诊断的应用是安全有效的。三维重建在肿瘤及周围淋巴结的术前评估中起着重要作用,可用于食管癌放疗和化疗远期疗效的评价。
Objective 3D reconstruction has been widely used in clinic,but there is only little research on the application of 3D reconstruction for the oesophagus.This research aims to study the application of 3D reconstruction in patients with lower segment oesophageal tumours to improve the diagnosis and treatment of oesophageal cancer and to provide a better method of preoperative assessment.Methods All the patients were treated at the First Hospital of Jilin University between January 2014 and August 2015 for oesophageal cancer.We collected the patients’ imaging data and used surface reconstruction technology to reconstruct their oesophageal tumours and adjacent structures.Tumour shape and other specific parameters were analysed and calculated,and comparisons of the results from different conditions of 3D reconstruction were made.IBM SPSS 19.0 was used to analyse all the data.All the data were averaged over three measurements.The t test was used to compare the mean of the two groups,and variance analysis was used among the groups,where P<0.05 indicated a significant difference.Results Of the 72 patients,there were 48 cases in which a gastroscope was able to pass through the oesophageal lesion and 24 cases where this was not possible.The location of the lesion ranged from 30 cm to 42 cm among those 48 cases.The endoscopic measurement length and the three-dimensional length were both longer than the pathological length(P<0.05),but there was no significant difference between the endoscopic measurement length and the three-dimensional length.In the reconstructed data of CT positive lymph nodes,the length,diameter,volume,CT value of the lymph nodes in the negative group were significantly different compared with the positive group.Conclusion The application of 3D reconstruction in oesophageal cancer is safe and effective.3D reconstruction plays an important role in preoperative evaluation of tumours and the surrounding lymph nodes and may be useful for evaluation of the long-term efficacy of radiotherapy and chemotherapy f
作者
马晓超
王盈舒
王瑞
刘桂华
崔有斌
MA Xiao-chao;WANG Ying-shu;WANG Rui(Second Department of Thoracic Surgery,The First Hospital of Jilin University;College of Art and Design,Changchun University of Technology)
出处
《中国实验诊断学》
2019年第2期203-206,共4页
Chinese Journal of Laboratory Diagnosis
关键词
食管癌
三维重建
诊断与治疗
Oesophageal cancer
3Dreconstruction
diagnosis and treatment
