摘要
本草基因组学是中药学与基因组学的交叉学科,是涵盖药用生物多组学研究和中药与人体相互多组学研究的综合性学科。在药用模式生物、中药合成生物学、中药分子鉴定和药用植物分子育种、药物体内过程组学、中药道地性和药性研究等领域得到了广泛应用,取得了一批标志性成果。随着《中华人民共和国中医药法》《中医药发展战略规划纲要(2016—2030年)》等重要文件的发布,中医药产业进入了全新的、高水平的发展机遇期,复合创新型研究人才的培养是中医药产业发展及医药专业高校教学改革面临的关键问题,该学科的建立对于中医药现代化发展尤为重要,已有多所高等院校开设《本草基因组学》课程,初步形成了特色鲜明的本草基因组学人才培养体系。该文从本草基因组学研究进展、教学开展情况、教材编写背景、主要内容及关键技术、学科特色、学科建设展望方面进行阐述,为本草基因组学的学科建设、人才培养和科学研究提供理论依据和方法学支撑。
Herbgenomics is an interdisciplinary subject between traditional Chinese medicine(TCM)and genomics.It is a comprehensive discipline covering multi-omics research in both medicinal organisms of TCM and the relationship of TCM to human body.It has been widely used in the research fields of medicinal model organisms,synthetic biology of TCM,identification of TCM molecules and breeding of medicinal plant cultivars,pharmacokinetics,and the study on the geoherbalism and medicinal of TCM.With the release of important documents,such as the Law of the People’s Republic of China on TCM and the Outline of TCM Development Strategy(2016—2030),the Chinese medicine industry has entered a new and high-level development opportunity and the herbgenomic research area has got a landmark achievement.The training of well-rounded students and researchers is a key point for the development of TCM industry and the reform of medical colleges and universities.Therefore,the establishment of herbgenomics is particularly important for the modernization of TCM.At present,many colleges and universities have set up the course of Herbgenomics among graduate students and undergraduates,and initially formed a distinctive herbal genomics talent training system.This paper introduces the herbgenomics from the progress of the research,the development of teaching courses,the background of the textbook,the main content and key technologies of the discipline and the prospect of discipline construction,in order to provide theoretical basis and methodological support for the discipline construction,personal training and scientific research of herbgenomics.
作者
张雪琼
徐宏喜
刘义飞
胡志刚
刘霞
ZHANG Xue-qiong;XU Hong-xi;LIU Yi-fei;HU Zhi-gang;LIU Xia(School of Chemistry,Chemical Engineering and Life Sciences,Wuhan University of Technology,Wuhan 430070,China;School of Pharmacy,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;School of Pharmacy,Hubei University of Chinese Medicine,Wuhan 430065,China)
出处
《中国实验方剂学杂志》
CAS
CSCD
北大核心
2019年第11期180-189,共10页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家自然科学基金项目(81130069)
武汉理工大学专业学位研究生团队指导项目(201701)
2018年湖北省高等学校省级教学研究项目(120)
武汉理工大学2019年研究生公共实验课程建设项目(6)
上海中医药大学第四期通识教育课程建设项目--本草基因组学
关键词
本草基因组学
基因组学
学科建设
DNA条形码
关键技术
分子辅助育种
全产业链
herbgenomics
genomics
discipline construction
DNA barcoding
key technologies
molecular assisted breeding
whole industrial chain
