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肿瘤患者尿路感染大肠埃希菌病原菌分布及耐药性 被引量:11

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摘要 目的探讨肿瘤患者尿路感染大肠埃希菌的病原菌分布及其耐药性分析。方法回顾性分析425例肿瘤患者送检标本分离到313株大肠埃希菌的相关资料。结果 425例肿瘤患者培养出细菌样本425例,其中313株(73.65%)为大肠埃希菌,其主要来源于尿道感染的前5位肿瘤疾病,即宫颈癌、直肠癌、肺癌、子宫内膜癌和卵巢癌;313例大肠埃希菌株中,产超广谱β-内酰胺酶(ESBLs)菌株160株(51.11%),大肠埃希菌对亚胺培南、美罗培南、环丙沙星耐药性最低,其次为他唑巴坦;对阿莫西林耐药性最高,其次为哌拉西林和替卡西林。结论肿瘤患者尿路感染大肠埃希菌病原菌分布广泛,对多数抗菌药物具有一定耐药性,但对亚胺培南、美罗培南与他唑巴坦耐药性较低,临床应注意抗菌药物的合理使用。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2015年第12期3329-3330,共2页 Chinese Journal of Gerontology
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