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嗅觉障碍与阿尔茨海默病的关系 被引量:2

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摘要 阿尔茨海默病(AD)患者出现精神紊乱、记忆逐步遗失、认知能力下降和行为功能减退的症状。该病的病理现象有Tau蛋白过度磷酸化引起的神经纤维原缠结、β-淀粉样蛋白沉积形成的老年斑(SP)及神经元大量凋亡。目前尚未开发出可以终止或逆转AD进程的药物〔1〕。如何尽早发现并确诊病例以便减缓病情的发展并对症治疗,已成为备受关注的问题〔2~4〕。越来越多的研究结果表明,嗅觉系统与AD存在极大相关性。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2015年第8期2288-2290,共3页 Chinese Journal of Gerontology
基金 国家自然科学基金面上项目(31471587) 北京市属高等学校高层次人才引进与培养三年行动计划(2013-2015年) 青年拔尖人才培育计划资助项目(CIT8TCD201504034)
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