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麝香保心丸对冠心病合并颈动脉粥样斑块患者血管内皮的影响 被引量:21

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摘要 目的探讨麝香保心丸(SXBXP)治疗冠心病合并颈动脉粥样斑块患者血管内皮的影响。方法选择80例冠心病合并颈动脉粥样斑块患者随机分为对照组(常规治疗)和治疗组(常规治疗基础上加服SXBXP)各40例,疗程8 w。比较两组肱动脉介导内皮依赖性舒张功能(FMD)、一氧化氮(NO)、内皮素(ET-1)、6-酮-前列腺素F1a(6-Keto-PGF-1a)、血栓素B2(TXB2)、血清肌酐(SCr)的情况。结果治疗结束后,治疗组FMD、NO、6-Keto-PGF-1a较同组治疗前及对照组治疗后均显著升高(P<0.05);ET-1、TXB2分别较同组治疗前及对照组均显著降低(P<0.05),另外SCr治疗前后无差异(P>0.05)。结论 SXBXP可以有效改善冠心病合并颈动脉粥样斑块患者的血管内皮功能。
作者 张莉 胡建华
出处 《中国老年学杂志》 CAS CSCD 北大核心 2015年第6期1507-1509,共3页 Chinese Journal of Gerontology
基金 恩施州科技局计划项目(No.2013-15-4)
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