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膳食纤维的抗炎作用 被引量:6

Anti-inflammatory effects of dietary fiber
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摘要 目的总结膳食纤维的定义及其生理功能,归纳其抗炎作用的机制。方法回顾近年来国内外发表的涉及膳食纤维定义、生理功能及其抗炎作用的中、英文文献。结果膳食纤维是不能被人体小肠消化、吸收的,由多种单体成分所形成的糖类聚合物。膳食纤维分为可溶性膳食纤维和不可溶性膳食纤维,其中可溶性膳食纤维能被肠道菌群代谢分解为短链脂肪酸。膳食纤维或短链脂肪酸通过影响机体炎症细胞的分化、炎症因子的表达、肠道菌群及肠黏膜屏障的功能,从而预防炎症的发生。结论膳食纤维具有一定的抗炎作用,但其具体机制尚需进一步研究。 Objective To summarize the deifnition and physiological function of dietary ifber and to conclude the mechanism of anti-inlfammatory effect.Methods We review the role of dietary ifber deifnition, physiological function and the mechanism of anti-inlfammatory effect in the domestic and foreign published literature in recent years.Results Dietary ifber is a kind of carbohydrate polymers, which is composed of a variety of monomer component and can't be digested or absorbed by small intestinal. It could be classiifed into soluble dietary ifber and insoluble dietary ifber, of which the former one can be decomposed into short chain fatty acids by gut lfora metabolism. Many recent studies have shown that dietary ifber or short chain fatty acids exerts a preventive effect on inlfammation by affecting differentiation of inlfammatory cells, expression of inlfammatory cytokines, intestinal lfora and intestinal mucosal barrier function.Conclusions Dietary fiber has certain function of anti-inflammatory, but much research is needed to explore the mechanism of the anti-inlfammatory effect of dietary ifber.
作者 陈会永 黄河
出处 《肿瘤代谢与营养电子杂志》 2015年第4期63-68,共6页 Electronic Journal of Metabolism and Nutrition of Cancer
基金 国家临床重点专科普通外科建设项目资金资助课题 山西省自然科学基金(2014011037-2) 山西医科大学第一医院院基金(YG1206)
关键词 膳食纤维 抗炎 Dietary fiber Anti-inflammatory
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  • 1Effect of butyrate enemas on inflammation and antioxidant status in the colonic mucosa of patients with ulcerative colitis in remission(J)Clinical Nutrition . 2010 (6) 被引量:1
  • 2Jihane Frikeche,Thomas Simon,Eolia Brissot,Marc Grégoire,Béatrice Gaugler,Mohamad Mohty.??Impact of valproic acid on dendritic cells function(J)Immunobiology . 2011 (7) 被引量:1
  • 3Ying Chen,Lei Dong,Dong Weng,Fangwei Liu,Laiyu Song,Cuiying Li,Wen Tang,Jie Chen.??1,3?β?Glucan affects the balance of Th1/Th2 cytokines by promoting secretionof anti?inflammatory cytokines in vitro(J)Molecular Medicine Reports . 2013 (2) 被引量:1
  • 4Patrick M. Smith,Michael R. Howitt,Nicolai Panikov,Monia Michaud,Carey Ann Gallini,Mohammad Bohlooly-Y,Jonathan N. Glickman,Wendy S. Garrett.??The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis(J)Science . 2013 (6145) 被引量:3
  • 5Milos Jesenak,Martin Hrubisko,Juraj Majtan,Zuzana Rennerova,Peter Banovcin.??Anti‐allergic Effect of Pleuran ( β ‐glucan from Pleurotus ostreatus ) in Children with Recurrent Respiratory Tract Infections(J)Phytother. Res. . 2014 (3) 被引量:1
  • 6Fermín Capitán‐Ca?adas,Mercedes Ortega‐González,Emilia Guadix,Antonio Zarzuelo,María Dolores Suárez,Fermín Sánchez Medina,Olga Martínez‐Augustin.??Prebiotic oligosaccharides directly modulate proinflammatory cytokine production in monocytes via activation of TLR 4(J)Mol. Nutr. Food Res. . 2014 (5) 被引量:1
  • 7Nagendra Singh,Ashish Gurav,Sathish Sivaprakasam,Evan Brady,Ravi Padia,Huidong Shi,Muthusamy Thangaraju,Puttur D. Prasad,Santhakumar Manicassamy,David H. Munn,Jeffrey R. Lee,Stefan Offermanns,Vadivel Ganapathy.Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis[J]. Immunity . 2014 (1) 被引量:2
  • 8张利利,郑鹏远,王新亭,刘志强,黄煌,罗予.双歧杆菌对食物过敏小鼠肠道屏障功能及Th1/Th2细胞因子的影响[J].世界华人消化杂志,2009,17(11):1091-1097. 被引量:28
  • 9Mary Ann Cox,James Jackson,Michaela Stanton,Alberto Rojas-Triana,Loretta Bober,Maureen Laverty,Xiaoxin Yang,Feng Zhu,Jianjun Liu,Suke Wang,Frederick Monsma,Galya Vassileva,Maureen Maguire,Eric Gustafson,Marvin Bayne,Chuan-Chu Chou,Daniel Lundell,Chung-Her Jenh.Short-chain fatty acids act as antiinflammatory mediators by regulating prostaglandin E_2 and cytokines[J].World Journal of Gastroenterology,2009,15(44):5549-5557. 被引量:33
  • 10董林,王艳萍,王金良,沈志强,谢金文.Foxp3结构、功能及其在机体免疫抑制中的作用[J].中国动物传染病学报,2010,18(6):74-78. 被引量:1

二级参考文献88

  • 1肖玲莉,杨毅.Th1/Th2免疫应答失衡及其影响因素[J].国际儿科学杂志,2006,33(6):399-402. 被引量:26
  • 2徐林,蒋正刚,李宝华,熊思东.小鼠乳腺癌实验动物模型中CD4^+ CD25^+调节性T细胞的变化及意义[J].复旦学报(医学版),2006,33(6):736-740. 被引量:13
  • 3黎君友,于燕,郝军,晋桦,许惠君.分光光度法测定血和小肠组织二胺氧化酶活性[J].氨基酸和生物资源,1996,18(4):28-30. 被引量:202
  • 4Kim H,Kwack K,Kim DY,Ji GE.Oral probiotic bacterial administration suppressed allergic responses in an ovalbumin-induced allergy mouse model.FEMS Immunol Med Microbiol 2005; 45:259-267 被引量:1
  • 5Kim H,Lee SY,Ji GE.Timing of bifidobacterium administration influences the development of allergy to ovalbumin in mice.Biotechnol Lett 2005;27:1361-1367 被引量:1
  • 6Jonkers D,Stockbrugger R.Review article:Probiotics in gastrointestinal and liver diseases.Aliment Pharmacol Ther 2007; 26 Suppl 2:133-148 被引量:1
  • 7Adel-patient K,Bernard H,Ah-Leung S,Creminon C,Wal JM.Peanut-and cow's milk-specific IgE,Th2 cells and local anaphylactic reaction are induced in Balb/c mice orally sensitized with cholera toxin.Allergy 2005; 60:658-664 被引量:1
  • 8Mucida D,Park Y,Kim G,Turovskaya O,Scott I,Kronenberg M,Cheroutre H.Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid.Science 2007; 317:256-260 被引量:1
  • 9Kedzierska A,Kaszuba-Zwoinska J,Slodowska-Hajduk Z,Kapinska-Mrowiecka M,Czubak M,Thor P,Wojcik K,Pryjma J.SEB-induced T cell apoptosis in atopic patients--correlation to clinical status and skin colonization by Staphylococcus aureus.Arch Immunol Ther Exp (Warsz) 2005; 53:63-70 被引量:1
  • 10Yang PC,Xing Z,Berin CM,Soderholm JD,Feng BS,Wu L,Yeh C.TIM-4 expressed by mucosal dendritic cells plays a critical role in food antigenspecific Th2 differentiation and intestinal allergy.Gastroenterology 2007; 133:1522-1533 被引量:1

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