摘要
目的总结膳食纤维的定义及其生理功能,归纳其抗炎作用的机制。方法回顾近年来国内外发表的涉及膳食纤维定义、生理功能及其抗炎作用的中、英文文献。结果膳食纤维是不能被人体小肠消化、吸收的,由多种单体成分所形成的糖类聚合物。膳食纤维分为可溶性膳食纤维和不可溶性膳食纤维,其中可溶性膳食纤维能被肠道菌群代谢分解为短链脂肪酸。膳食纤维或短链脂肪酸通过影响机体炎症细胞的分化、炎症因子的表达、肠道菌群及肠黏膜屏障的功能,从而预防炎症的发生。结论膳食纤维具有一定的抗炎作用,但其具体机制尚需进一步研究。
Objective To summarize the deifnition and physiological function of dietary ifber and to conclude the mechanism of anti-inlfammatory effect.Methods We review the role of dietary ifber deifnition, physiological function and the mechanism of anti-inlfammatory effect in the domestic and foreign published literature in recent years.Results Dietary ifber is a kind of carbohydrate polymers, which is composed of a variety of monomer component and can't be digested or absorbed by small intestinal. It could be classiifed into soluble dietary ifber and insoluble dietary ifber, of which the former one can be decomposed into short chain fatty acids by gut lfora metabolism. Many recent studies have shown that dietary ifber or short chain fatty acids exerts a preventive effect on inlfammation by affecting differentiation of inlfammatory cells, expression of inlfammatory cytokines, intestinal lfora and intestinal mucosal barrier function.Conclusions Dietary fiber has certain function of anti-inflammatory, but much research is needed to explore the mechanism of the anti-inlfammatory effect of dietary ifber.
出处
《肿瘤代谢与营养电子杂志》
2015年第4期63-68,共6页
Electronic Journal of Metabolism and Nutrition of Cancer
基金
国家临床重点专科普通外科建设项目资金资助课题
山西省自然科学基金(2014011037-2)
山西医科大学第一医院院基金(YG1206)
关键词
膳食纤维
抗炎
Dietary fiber
Anti-inflammatory