摘要
目的调查并分析幽门螺杆菌培养呈阳性的患者的耐药情况,并且对患者的临床治疗进行探讨,总结有效的治疗方法。方法选择我院在2015年10月到2017年4月接收的通过幽门螺杆菌培养呈阳性的患者作为本研究的研究对象,共涉及到患者80例,对所有患者均进行菌株分离的处理,同时选择采用E-test方法测定Hp对甲硝唑、克拉霉素和阿莫西林药物的敏感性,综合应用三联疗法治疗一周和四联疗法治疗3日对患者进行根治性治疗,分析临床治疗的结果。结果幽门螺杆菌对于三种药物都表现出了一定程度的耐药性,通过为期一周的三联疗法和为期3日的四联疗法对于幽门螺杆菌感染患者进行治疗,幽门螺杆菌的根治率是存在明显差异的。结论幽门螺杆菌本身就具有显著的抗菌耐药性特点,抗菌耐药性的严重和剧烈程度与临床实际所获取的根治率存在有明显的相关性,在对患者进行临床治疗的时候,应该对此予以重视,根据患者实际情况为患者选择合适的方法进行治疗。
Objective To investigate and analyze drug resistance of positive helicobacter pylori infected patients, and explore clinical treatment and summarize effective treatment methods. Methods Choose 80 helicobacter pylori cultured positive patients received in our hospital from October 2015 to April 2017 as research objects, treat them with strain isolation, and determine sensitivity of Hp for metronidazole, clarithromycin and amoxicillin by E-test method, carry on radical treatment with triple therapy for one week and quadruple therapy for 3 days, analyze clinical treatment effect. Results Helicobacter pylori showed some certain resistance for three kinds of medince, triple therapy for one week and quadruple therapy for 3 days for helicobacter pylori infected patients showed, radical rate of helicobacter pylori showed difference.Conclusion Helicobacter pylori itself has significant antibacterial drug resistance, and severe intense degree is significantly correlated to clinical actual radical rate during clinical treatment, it should be paid attention, choose appropriate treatment method according to actual situation of patients.
出处
《智慧健康》
2017年第12期97-99,共3页
Smart Healthcare
关键词
幽门螺杆菌
培养阳性
耐药性
Helicobacter pylori
Culture positive
Drug resistance
