摘要
目的研究蒙药嘎日迪-5用于妇科腹腔镜手术超前镇痛的效果。方法采用随机双盲对照试验设计,择期妇科腹腔镜手术的患者60例,随机分为实验组和对照组,每组30例。实验组于术前20-22h,4-6h及术后6h各口服嘎日迪-5丸2克;对照组服无药效的安慰剂。使用视学模拟评分法(VAS)和舒适度评级(BCS)评定并比较两组患者术后疼痛程度,对镇痛药物追加使用的剂量、时间进行记录,对患者各项生命体征指标进行记录,并比较两组下床活动时间及不良反应。结果在手术后0、2、4、8、12小时,实验组患者BCS评分、VAS评分,与对照组相比,均具有显著差异(P<0.05)。且实验组患者下床活动时间也与对照组存在显著差异(P<0.05)。在术后不良反应方面,两组患者无显著差异(P>0.05)。术后因镇痛不全需追加镇痛药物,实验组患者用药量低于对照组患者(P<0.05)。在不良反应发生率上,两组患者无显著差异(P>0.05)。结论在妇科腹腔镜手术的超前镇痛中,使用蒙药嘎日迪-5,临床效果确切。
Objective To study effect of Mongolian medicine Garidi-5 for preemptive analgesia of gynecological laparoscopic surgery. Methods with randomized, double blind and controlled experiment design, choose 60 cases with gynecological laparoscopic surgery, divide them into experimental and control groups randomly, 30 cases in each. Experimental group was treated with oral administration of Garidi-5 pills 2 grams 20-22 h, 4-6h before operation and 6h after operation; control group with non-effective placebo. With visual analogue scale(VAS) and Bruggrmann comfort scale(BCS), evaluate and compare postoperative pains degree, record additional dose of analgesic medicine, time and vital signs of patients of two groups, and compare ambulation time and adverse reaction of two groups. Results pains disappeared 0, 2, 4, 8 and 12 h after operation, and BCS and VAS scores of experimental group were significantly different from control group(P<0.05). And ambulation time of experimental group was also significantly different from control group(P<0.05). Postoperative adverse reactions showed no significant difference between two groups,(P>0.05). For postoperative analgesia insufficiency, it is necessary to add analgesic medicine, and dosage of experimental group was less than control group(P<0.05). Adverse reaction incidence showed no significant difference between two groups(P>0.05). Conclusion Mongolian medicine Garidi-5 has exact clinical effect for preemptive analgesia of gynecological laparoscopic surgery.
出处
《智慧健康》
2017年第9期55-56,59,共3页
Smart Healthcare
关键词
蒙药嘎日迪-5
超前镇痛
妇科腹腔镜手术
Mongolian medicine Garidi-5
Preemptive analgesia
Gynecological laparoscopic surgery
