摘要
随着影像学和诊断技术的进步,胰腺神经内分泌肿瘤检出率增长迅速。但因其临床表现多样,误诊率高,治疗手段复杂,诊治指南相对不完善,给临床实践造成了很大困扰。尤其是在外科治疗方面,保留胰腺功能和标准清扫肿瘤术式之间难以取舍,针对直径<2 cm的肿瘤更存在巨大争议。而在选择术式的同时,是否要行淋巴结清扫仍是另一个悬而未决的问题。由于很难开展随机对照研究,针对此问题的研究多为跨度长、基于公共数据库的回顾性研究,其受时间、不同地区医疗水平和术者等因素影响较大,混杂因素较多,得出的结论不一。
In recent years,with the progress of imaging and diagnostic technology,the detection rate of pancreatic neuroendocrine neoplasms has increased rapidly.However,its clinical manifestations are diverse,the rate of misdiagnosis is high,the therapeutic treatments are complex,and the guidelines for diagnosis and treatment are relatively imperfect,which has caused great trouble in clinical practice.Especially in surgical treatment,it is difficult to choose between preservation of pancreatic function and standard radical resection,especially for tumors less than 2 cm.At the same time,whether lymph node resection should be performed is another open question.Because it is difficult to carry out randomized controlled studies,most of the studies on this issue are long-span retrospective studies based on public databases,which are greatly influenced by factors such as time,medical level in different regions and different surgeons.It is the confounding factors that lead to inconsistent results.
作者
郭世伟
金钢
GUO Shi-wei;JIN Gang(Department of Hepato-Biliary-Pancreatic Surgery,Changhai Hospital,Navy Medical University,Shanghai 200433,China)
出处
《中国实用外科杂志》
CSCD
北大核心
2019年第9期917-921,共5页
Chinese Journal of Practical Surgery
关键词
胰腺神经内分泌肿瘤
根治性切除
淋巴结清扫
预后
pancreatic neuroendocrine neoplasms
radical resection
lymphadenectomy
prognosis
