摘要
目的探讨血清人绒毛膜促性腺激素(β-h CG)联合超敏C-反应蛋白(hs-CRP)水平对产前羊膜腔感染的预测价值。方法随机选取2017年收入汕头市妇幼保健院产科住院并分娩的180例孕妇作为研究对象,其中胎膜早破孕妇100例,以胎盘胎膜病理诊断作为羊膜腔感染的金标准,分为宫内感染组46例,非宫内感染组54例,余非胎膜早破的孕妇80例作为对照组。分组比较所有孕妇的血β-h CG和hs-CRP值。结果胎膜早破孕妇的血清β-h CG和hs-CRP水平明显高于对照组,差异有统计学意义(P<0. 05);其中宫内感染组血清β-h CG和hs-CRP水平显著高于非宫内感染组,且随着感染程度的加重而明显升高,差异有统计学意义(P<0. 05)。结论联合血清β-h CG和hs-CRP水平能更有效地早期预测羊膜腔感染的发生及评估感染程度,可为基层医院临床医生早期诊断胎膜早破羊膜腔感染提供经济而有效的检测手段。
Objective To explore the predictive value of serum human chorionic gonadotropin( β-h CG) combined with high-sensitivity C-reactive protein( hs-CRP) for prenatal intraamniotic infection. Methods A total of 180 pregnant women giving birth to their babies in Department of Obstetrics,Shantou Municipal Maternal and Child Health Care Hospital in 2017 were randomly selected,including 100 pregnant women with premature rupture of fetal membranes( PROM) and 80 pregnant women without PROM( control group),100 pregnant women with PROM were divided into intrauterine infection group( 46 pregnant women) and non-intrauterine infection group( 54 pregnant women) using pathological diagnosis of placenta and fetal membrane as gold standard of intraamniotic infection. The levels of serum β-h CG and hs-CRP were compared among different groups. Results The levels of serum β-h CG and hs-CRP in PROM group were statistically significantly higher than those in control group( P< 0. 05). The levels of serum β-h CG and hs-CRP in intrauterine infection group were statistically significantly higher than those in non-intrauterine infection group,which increased significantly with aggravation of infection degree( P<0. 05). Conclusion Combined detection of serum β-h CG and hs-CRP can effectively predict the occurrence of intraamniotic infection and assess the degree of infection,which can provide economical and effective detection method for early diagnosis of intraamniotic infection among PROM pregnant women in primary hospitals.
作者
李冬红
彭秀玲
马琼霞
LI Dong-Hong;PENG Xiu-Ling;MA Qiong-Xia(Department of Gynecology and Obstetrics,Shantou Municipal Maternal and Child Health Care Hospital,Shantou,Guangdong515041,China)
出处
《中国妇幼保健》
CAS
2019年第3期512-514,共3页
Maternal and Child Health Care of China
关键词
胎膜早破
血清人绒毛膜促性腺激素
超敏C-反应蛋白
羊膜腔感染
Premature rupture of fetal membranes
Serum β-hCG
High-sensitivity C-reactive protein
Intraamniotic infection
