摘要
目的运用Meta分析方法评价穴位埋线治疗慢性阻塞性肺疾病(COPD)稳定期的有效性。方法通过文献数据库检索穴位埋线治疗COPD稳定期的所有随机对照试验(RCT),以总有效率,肺功能FEV1、FEV1/FVC、FEV1%,CAT评分,mMRC评分,6MWT作为结局指标进行Meta分析。结果共纳入17篇随机对照试验,共1519例患者。经Meta分析,其中有效性分析结果表明在提高治疗后总有效率、肺功能FEV1%,改善CAT评分、mMRC评分、6MWT方面治疗组优于对照组,差异有统计学意义(P<0.05);在提高治疗后肺功能FEV1、FEV1/FVC方面治疗组与对照组差异无统计学意义(P>0.05)。安全性分析结果表明穴位埋线安全性良好。结论穴位埋线治疗COPD稳定期安全有效。本研究纳入研究数量偏少,异质性大,证据强度不高,仍需设计高质量临床试验深入研究。
Objective To evaluate the efficacy of acupoint embedding in the stable period of chronic obstructive pulmonary disease(COPD)with Meta-analysis.Methods Randomized controlled trial(RCT)of acupoint catgut embedding therapy for COPD in stable period were retrieved through literature database.Meta-analysis was conducted with total effective rate,pulmonary function FEV1,FEV1/FVC,FEV1%,CAT score,mMRC score and 6 MWT as outcome indicators.Results A total of 17 randomized controlled trials involving a total of 1 519 patients were included.According to the Meta-analysis,the results of the effectiveness analysis showed that the total effective rate,pulmonary function FEV1%,improvement of CAT score,mMRC score,and 6 MWT in the treatment group were better than those in the control group,the differences were statistically significant(P<0.05);in the improvement of pulmonary function FEV1,FEV1/FVC after treatment,there were no significant differences between treatment group and control group(P>0.05).The result of safety analysis showed that acupoint embedding at acupoints was safe.Conclusion Acupoint embedding therapy is safe and effective in the treatment of COPD.The number of studies included in this study is small,heterogeneity is large,and the intensity of evidence is not high.It is still necessary to design high-quality clinical trials for further research.
作者
远颖
YUAN Ying(Department of Pulmonary Disease,Tianjin Institute of Traditional Chinese Medicine,Tianjin 300120,China)
出处
《中国城乡企业卫生》
2019年第5期22-27,共6页
Chinese Journal of Urban and Rural Enterprise Hygiene
关键词
穴位埋线
慢性阻塞性肺疾病
有效性
安全性
META分析
Acupoint embedding
Chronic obstructive pulmonary disease
Effectiveness
Safety
Meta-analysis
