摘要
目的调查中国北方汉族与维吾尔族群体8个STR位点的遗传多态性。方法应用荧光标记引物试剂盒及基因扫描技术检测vWA、TH01、TPOX、CSF1PO、D5S818、D13S317、D7S820、D16S539位点等位基因。结果100例汉族群体共检出62个等位基因,累计非父排除率为0.9975;50例维吾尔族群体共检出52个等位基因,累计非父排除率为0.9973。2群体总个人识别机率均超过0.9999。基因频率分布2群体间存在显著性差异。结论8个STR位点在汉族与维吾尔族群体中具有较高的遗传多态性,频率分布有民族差别。
Objective The genetic polymorphism of8STR loci,was studied in northern Chinese Han and Uygur populations.Methods The8STR loci(vWA,TH01,TP0X,CSF1P0,D5S818,D13S317,D7S820,D16S539)were analyzed and genotyped by fluorescent prime labeling kit and gene scan technology.Results62alleles were found in100individuals of Han population,CPE value was0.9975;And52alleles were found in50individuals of uygur population,CPE value was0.9973.The TDP of both was beyond0.9999.The difference of gene frequency between the two populations was significant.Conclusion The genetic polymorphism of the8STR loci in the Han and uygur populations is high,there are ethic differences in frequency distribution.
出处
《法医学杂志》
CAS
CSCD
2003年第3期149-150,153,共3页
Journal of Forensic Medicine
