摘要
目的 :模仿椎体成形术观察注射型磷酸钙骨水泥 (calcium phosphatecementCPC) /聚甲基丙烯酸甲酯(polymethylmethacrylate ,PMMA)植入椎体后的生物力学改变。方法 :将PMMA和CPC通过手术植入到犬椎体 ,经过 8周和 16周后分别取材 ,行X线、CT检查 ,并测定不同时间椎体的轴向抗压强度和抗扭转强度。结果 :( 1)植入早期 ,PMMA的抗压强度明显高于正常椎体和CPC (P <0 0 1) ,CPC的抗压强度明显低于正常椎体和PMMA (P<0 0 1)。术后 8周显示 ,PMMA的抗压强度有所下降 (P <0 0 1=0 0 0 9) ,CPC的抗压强度有所上升 (P <0 0 5 =0 0 3 4) ,但与正常椎体相比仍差别显著。术后 16周显示PMMA抗压强度继续下降 (P >0 0 5 =0 710 ) ,CPC的抗压强度继续上升 (P >0 0 5 =0 64 8) ,与正常椎体相比无显著性差异。 ( 2 )植入早期 ,PMMA的抗扭转强度明显高于正常椎体和CPC (P <0 0 5 =0 0 3 ) ,CPC的抗扭强度明显低于正常椎体和PMMA (P <0 0 5 =0 0 2 )。术后 8周显示 ,PMMA的抗扭强度有所下降 ,但与正常椎体相比仍差别显著 (P <0 0 5 =0 0 45 ) ,CPC的抗压强度有所上升与正常椎体相比差异不显著 (P >0 0 5 =0 0 78)。术后 16周显示PMMA抗压强度继续下降 (P >0 0 5 =0 13 7) ,CPC的抗压强度继续上升 ,与正?
Objective:To compare the differences of the biomechanical changes of calcium phosphate cement(CPC) and polymethylmethacrylate (PMMA)in implanting vertebral body in vertebroplasty.Methods:CPC and PMMA was implanted into vertebral body,the vertebral bodies implanted with CPC and PMMA at different stages were tested by axial compressive testing and torsional testing.Results:1.At early stages,vertebral bodies implanted with PMMA were stronger than normal vertebral bodies as well as vertebral bodies implanted with CPC (P<0.01) in compressive testing,while the stiffness of vertebral bodies implanted with CPC was weaker than that of normal vertebral bodies as well as vertebral bodies implanted with PMMA(P<0.01).After 8 weeks,the stiffness of vertebral bodies implanted with PMMA became low (P<0.01 =0.009),while the stiffness of vertebral bodies implanted with CPC became strong (P<0.05=0.034),but still significantly different from that of normal vertebral bodies.When it came to the 16th week,the stiffness of vertebral bodies implanted with PMMA became low (P>0.05=0.710),while the stiffness of vertebral bodies implanted with CPC became strong (P>0.05 = 0.648 ),and there were no significantly differences between them and that of normal vertebral bodies.2.At early stages,vertebral bodies implanted with PMMA were stronger than normal vertebral bodies as well as vertebral bodies implanted with CPC (P<0.05=0.03) in torsional testing,while the stiffness of vertebral bodies implanted with CPC was weaker than that of normal vertebral bodies as well as vertebral bodies implanted with PMMA (P<0.05=0.02).After 8 weeks,the stiffness of vertebral bodies implanted with PMMA became low(P<0.05=0.045),while the stiffness of vertebral bodies became strong (P>0.05=0.078),and had no significant differences from that of normal vertebral bodies.When it came to the 16th week,the stiffness of vertebral bodies became low (P>0.05 =0.137),while the stiffness of vertebral bodies became strong (P>0.05=0.847),and there were no significant differences b
出处
《中国矫形外科杂志》
CAS
CSCD
2004年第1期70-73,共4页
Orthopedic Journal of China
