摘要
目的建立大鼠胰腺移植模型.方法采用经肠道引流全胰十二指肠移植术式;带腹腔动脉和肠系膜上动脉的腹主动脉管与受体腹主动脉端侧吻合,供体门静脉与受体左肾静脉袖套法吻合,供体十二指肠与受体十二指肠端侧吻合.结果89只大鼠手术中51例手术成功,术后移植胰腺具有内分泌功能.结论这种胰腺移植模型制作方法切实可行.
Objective To establish the model of pancreaticoduodenal transplantation in rats as a contribution to the experimental therapy of diabetes. Methods The enteric drained whole pancreas duodenal transplantation model was adopted. The donor aortic segment including the celiac and superior mesenteric divergences was end-to-side anastomosed with recipient abdominal aorta. The donor portal was cuff-anastomosed with the left renal vein. And the graft duodenum was end-to-side anastomosed with the host jejunum. Results Out of the 89 operations performed, 51 were successful, in all of which the endocrinal function was secured. Conclusion This method for pancreas transplantation is practicable.
出处
《徐州医学院学报》
CAS
2003年第2期205-206,共2页
Acta Academiae Medicinae Xuzhou
