摘要
目的 :了解人类免疫缺陷病毒 (HIV)感染者中HIV感染途径、HIV/HBV及HIV/HCV合并感染情况和机会性感染的发生率及类型。方法 :检测HIV感染者 /获得性免疫缺陷综合征 (AIDS)患者HBV、HCV感染标志 ,确定HIV/HBV、HIV/HCV合并感染情况 ,了解其HIV感染途径 ,对是否存在机会性感染情况进行临床和实验室指标的综合诊断。结果 :5 5例HIV感染者中静脉吸毒、性接触、输血或血制品及垂直传播分别占 4 0 %、36 .4 %、2 0 .0 %及 3.6 %。HIV/HBV、HIV/HCV合并感染率分别为 16 .4 %和 4 1.8% ,两者比较有显著差异。机会性感染发生率为 85 .5 % ,感染类型由高至低依次为 :肺炎、口腔毛状黏膜白斑 (OHL)、口腔真菌感染、各种感染性腹泻、各种结核病、败血症、疱疹病毒感染。结论 :广州地区HIV感染途径由高到低的顺序为 :静脉吸毒传播、性传播、输血或血制品传播、母婴传播 ,其中以静脉吸毒和性接触方式感染为主。广州地区存在HIV/HBV、HIV/HCV合并感染情况 ,尤其是HIV/HCV合并感染率情况较严重 ;
Objective: To investigate HIV infection paths, co-infection of HIV/HBV and HIV/HCV, opportunistic infection rate and types in HIV infectors in Guangzhou. Methods: The paths of HIV infection were investigated. Opportunistic infection of above HIV infectors were diagnosed by connecting clinical symptoms and laboratory results. Results: The paths of HIV infection in above cases were respectively intravenous drug use (40%), sexual contact (36.4%), transfusion of blood or blood products (20.0%), mother-to-child transmission (3.6%). Co-infection ratio of HIV/HBV and HIV/HCV were respectively 16.4% and 41.8%, between which there was remarkable difference. Ratio of occurred opportunistic infection was 85.5%. The types of opportunistic infection in sequence from high to low incidence are: pneumonia, oral hairy leukoplakia (OHL), oral candidiasis, infectious diarrhea, tuberculosis, anemia, herpesvirus infection.Conclusion:In guangzhou, HIV infection paths in sequence from high to low rate are: intravenous drug use, sexual contact, transmission of blood or blood products, mother-to-child transmission, among which, intravenous drug use and sexual contact are the two main paths. HIV/HBV or HIV/HCV co-infection has occurred in HIV infectors, especially, HIV/HCV co-infection. AIDS with opportunistic infection has developed in majority of out patients with HIV infection in Guangzhou.
出处
《中国临床医学》
2003年第4期446-447,共2页
Chinese Journal of Clinical Medicine
基金
广州市科委重大科技攻关项目资助 (编号 :2 0 0 1-Z -0 2 3 -0 1)
