摘要
目的 应用共焦激光扫描显微镜观察及研究黄斑中心凹毛细血管拱环、中心凹无血管区( foveal avascular area,FAZ)的大小及其与年龄增长的关系。 方法 32只尸体眼黄斑部视网膜分离后 ,应用 型胶原抗体对视网膜血管进行免疫染色 ,采用共焦激光扫描显微镜观察结果 ,分析 FAZ的面积、直径与年龄的关系。 结果 清晰地观察到旁中央凹毛细血管网。FAZ的平均面积 ( 0 .2 4± 0 .13) mm2 ,平均直径 ( 0 .5 4± 0 .15 ) mm。FAZ的面积、直径与年龄无明显相关关系。 结论 共焦激光扫描显微镜与免疫染色法可清晰显示黄斑中心凹毛细血管拱环。FAZ的大小与年龄无明显关系。黄斑部毛细血管拱环完整性可能不受年龄影响。
ObjectiveTo observe the dimensions of the capillary blood vessel arch in central fovea of macula and the foveal avascular area (FAZ), and their relationships with age. MethodsRetina in macula of 32 cadavers eyes were isolated. Retinal vessels were immunostained by collagen type IV and examined by confocal laser scanning microscopy. The area and diameter of the FAZ were measured, and the relationship between FAZ and age was analysed. ResultsThe parafoveolar capillary network was observed clearly by confocal laser scanning microscopy. The average area of the FAZ was (0.24±0.13) mm2, and the average diameter was (0.54±0.15) mm. The area and diameter of the FAZ did not show any correlation with age. ConclusionsThe parafoveolar capillary network could be observed by confocal laser scanning microscopy. The size of the FAZ does not change with age. The dimensions of the parafoveolar capillary network may not be influenced by age.
出处
《中华眼底病杂志》
CAS
CSCD
2003年第2期73-75,共3页
Chinese Journal of Ocular Fundus Diseases
基金
国家教育部留学归国人员科研启动基金 (1 999)
