摘要
本实验以游泳训练的大鼠为实验模型,观察雄性SD大鼠心肌GSH、GSSG的含量以及GSH/GSSG的比值。发现经10周递增负荷的游泳训练和长时间力竭运动后,大鼠心肌GSH含量显著下降,GSSG的含量显著升高,心肌的GSH/GSSG的比值降低,P<0.05,提示长时间力竭运动致活性氧产生增加,GSH/GSSG氧化还原缓冲作用改变的可能性增加,影响了细胞信号传递过程。发现心肌GSH含量有下降趋势。本实验还观察了大鼠心肌中巯基含量,发现巯基与GSH的变化相一致,从侧面反映运动导致机体活性氧产生增加,细胞氧化还原状态发生改变的可能性增加。
The effects of 10 weeks progressive training and exhaustive exercise on GSH, GSSG content and GSH/GSSG ratio were studied in heart of rats. After one time exhausted exercise glutathione in heart was significant decreased, GSSG content increased and GSH/GSSG ration in heart significantly decreased. These results suggest that reactive oxygen species be generated during strenuous exercise as a result of the increased oxygen consumption. Heart GSH content had a tendency of decrease after 10 weeks progressive training.
出处
《成都体育学院学报》
CSSCI
北大核心
2004年第1期75-78,共4页
Journal of Chengdu Sport University
