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儿童维生素B_(12)缺乏症的研究进展

Progress in Vitamin B_(12) Deficiency in Children
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摘要 儿童因其生理、病理特点,发生维生素B12(VB12)缺乏时其临床症状和预后不同于成人。儿童VB12缺乏典型症状临床少见,而常表现为一些非典型症状。该症的非典型血液系统改变和不可逆的神经精神改变影响儿童体格和神经系统的正常发育,故儿童VB12缺乏症逐步受到人们的重视。诊断维生素B12(VB12)缺乏症经典的方法主要依赖血液系统出现巨幼红细胞性贫血,或者依据中性粒细胞分叶过多诊断轻度VB12缺乏。近年由于实验室技术的发展出现新的诊断亚临床VB12缺乏的检测方法。该文综述了近年来儿童VB12的吸收及代谢,VB12缺乏症的病因、非典型VB12缺乏症的临床表现和诊断方面的研究进展。 Previously,macrocytic anemia or hypersegmentation of neutrophilic leukocyte had been assumed to be classic diagnostic methods of vitamin B12 deficiency.However,there have been new diagnostic methods of marginal vitamin B12 deficiency due to developments of laboratory technique.Advanced diagnostic methods and progress in recent years about vitamin B12 deficiency have been reviewed in this text.
出处 《营养健康新观察》 2007年第1期44-48,共5页 Nutrition Newsletter
关键词 维生素B12缺乏 贫血 诊断 vitamin B12 (VB12) deficiency diagnosis
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参考文献11

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