摘要
目的探究妊娠期并发肿瘤对孕妇分娩结局及新生儿的影响。方法回顾性分析2010年2月至2013年2月青岛市胶州中心医院产科收治的40例妊娠期并发肿瘤患者(研究组)的临床资料,选择同期健康孕妇40例作为对照组。调查询问及随访搜集两组受试者的资料,了解妊娠期并发肿瘤的诊断、治疗情况以及分娩结局、新生儿状况等。结果继续妊娠组22例,终止妊娠组18例数。继续妊娠组发病到诊断时间、终止妊娠时间均长于终止妊娠组[(3.6±0.5)周比(1.2±0.6)周;(34.7±2.4)周比(22.4±9.6)周],差异有统计学意义(P<0.01)。继续妊娠组剖宫产、产后出血及产褥发生率显著高于对照组[81.8%(18/22)比27.5%(11/40);36.4%(8/22)比5.0%(2/40);22.7%(5/22)比5.0%(2/40)],差异有统计学意义(P<0.05);继续妊娠组早产儿、体质量偏低、新生儿窒息的发生率均明显高于对照组[54.5%(12/22)比7.5%(3/40);27.3%(5/22)比5.0%(2/40);18.2%(4/22)比2.5%(1/40)],差异有统计学意义(P<0.05)。结论妊娠期并发肿瘤对孕期妇女及新生儿的健康均有重大影响,直接影响孕妇的生存,但终止妊娠并不能延长孕妇生存时间;若继续妊娠还会导致剖宫产率及产后出血率的升高,新生儿易发早产与发育不良。
Objective To study the impact of tumors in pregnancy for the birth outcomes of the maternal and neonatal. Methods Retrospective analysis was used to study 40 cases( study group) of pregnancy with tumors admitted to Qingdao City Jiaozhou Central Hospital from Feb. 2010 to Feb. 2013,and 40 healthy pregnant women during the same period were chosen as a control group. The medical records of the two groups were collected by investigation and follow-up in order to know more about the diagnosis,treatment of the tumors,and birth outcomes and neonatal status for comparative study. Results The study group included continuing pregnancy group of 22 cases and terminating pregnancy group of 18 cases. The onset to diagnosis time and pregnancy termination time of the continuing pregnancy group were longer than terminating pregnancy group[( 3. 6 ± 0. 5) weeks vs( 1. 2 ± 0. 6) weeks;( 34. 7 ± 2. 4) weeks vs( 22. 4 ± 9. 6) weeks],the differences was statistically significant( P < 0. 01). Incidence of Cesarean section,postpartum hemorrhage and puerperal morbidity of the continuing pregnancy group were significantly higher than the control group[81. 8%( 18 /22) vs 27. 5%( 11 /40); 36. 4%( 8 /22) vs 5. 0%( 2 /40); 22. 7%( 5 /22) vs 5. 0%( 2 /40); P < 0. 05]. Incidence of premature infant,low body weight,neonatal asphyxia of the continuing pregnancy group were significantly higher than the control group[54. 5%( 12 /22) vs 7. 5%( 3 /40); 27. 3%( 5 /22)vs 5. 0%( 2 /40); 18. 2%( 4 /22) vs 2. 5%( 1 /40),P < 0. 05]. Conclusion There is a significant impact of tumors on pregnancy on the maternal and neonatal health,which directly impacts the maternal survival,however,termination of pregnancy cannot prolong the survival time at all. As the result of continued pregnancy,there are increasing rate of cesarean and postpartum hemorrhage,and preterm neonates and hypoplasia are more often.
出处
《医学综述》
2016年第10期2027-2029,共3页
Medical Recapitulate
