摘要
目的探讨重型颅脑外伤患者经纳洛酮联合醒脑静治疗的临床疗效。方法选取我院2014年5月至2016年5月收治的96例重型颅脑外伤患者为研究对象,将入选对象按照随机数字表法分为观察组与对照组(各48例),对照组给予单纯纳洛酮治疗,观察组给予纳洛酮联合醒脑静治疗,比较两组患者临床效果。结果经临床治疗,观察组患者清醒时间、清醒率均明显优于对照组,GCS、GOS评分也明显优于对照组;观察组患者治愈率为37.50%,临床总有效率为83.33%,而对照组患者治愈率为22.92%,临床总有效率为68.75%,观察组治愈率及总有效率高于对照组,组间差异均有统计学意义(P<0.05);两组不良反应情况比较无显著性差异。结论纳洛酮联合醒脑静治疗重型颅脑外伤疾病可促使患者快速苏醒,恢复神经系统功能,安全性高,值得临床推广应用。
Objective To analyze the clinical effect of naloxone combined with Xingnaojing injection in the treatment of severe craniocerebral injury. Methods Ninety-six cases of severe traumatic brain injury from May 2014 to May 2016 were selected as the research object, the patients were randomly divided into observation group and control group, 48 cases in each group. The patients in control group were given naloxone treatment alone, the patients in observation group were given naloxone combined with Xingnaojing treatment, then the clinical results was compared. Results After clinical treatment,awake time and sober rate in the observation group were significantly better than the control group, GCS, GOS score were also significantly better. The cure rate in the observation group was 37.50% and the total clinical effective rate was83.33%, while in the control group of 22.92% and 68.75% respectively, the cure rate and the total efficiency in the observation group were higher than those of the control group(P <0.05); the adverse reaction between the two groups had no significant difference. Conclusion The treatment of naloxone combined with Xingnaojing in the treatment of restoring consciousness for severe traumatic brain injury diseases can quickly shorten the patient awake time, recover nervous system damage function, which is worthy of clinical application.
出处
《临床医学研究与实践》
2016年第18期9-10,13,共3页
Clinical Research and Practice
