摘要
目的:分析早期胃癌临床病理学特点,探讨早期胃癌病理学诊断及形态学发生机制.方法:回顾性分析江汉大学附属医院1988～2003年手术切除经病理诊断确诊有完整资料的早期胃癌24例,分别观察肿瘤的发生部位、肉眼分型、浸润深度、肿瘤大小、组织学分类、多灶性、伴随病变以及淋巴结转移程度等各项病理学指标.结果:早期胃癌好发于胃窦区及小弯侧,溃疡型多见;粘膜内癌的瘤灶小于粘膜下癌;组织学分类以管状型腺癌为主,常与慢性萎缩性胃炎、不典型增生和肠上皮化生相伴随;4例早期胃癌呈现多灶性;全组早期胃癌淋巴结转移率29.2%.结论:①详细规范的病理学检查对早期胃癌的病理学诊断具有重要意义;②早期胃癌的浸润深度、肿瘤大小、伴随疾病及淋巴结转移的数据是早期胃癌病理学诊断的重要指标.
Objective: To discuss the pathological diagnosis and morphological occurrence by investigating the clinical pathological features of early gastric cancer (EGC). Methods: We inves- tigated the morphological features of 24 EGC with integral data which were resected and final diagnosis at our affiliated hospital from 1988 to 2003, including the locus, macroscopic appearance, depth of invasion, size, histology, multiple simuttneous, lymph node metastasis, and following disease. Results: EGC often origins from antrum and little curvature of stomach; comparing with submucosal cancers, cancers mucosal cancers is smaller in size; the classification of histology usually is tube adenocarcinoma ; EGC usually is followed by chronic atrophic gastritis, atypical hyperplasia and intestinal metaplasia. Conclusion: The detection of depth of invasion, size, histology, frequency of lymph node invasion, and following disease is very important to the pathological diagnosis of EGC.
出处
《江汉大学学报（自然科学版）》
2003年第4期76-78,84,共4页
Journal of Jianghan University：Natural Science Edition
