摘要
目的采用Meta分析系统评价腹腔镜联合胆道镜钬激光治疗胆管结石的疗效。方法检索CNKI、万方、维普、Web of science和PubMed数据库中近5年(2013年‐2018年)发表的关于腹腔镜联合胆道镜钬激光与开腹术治疗胆管结石的随机对照研究的文献,按照纳入标准筛选文献,提取资料利用Review Manager 5.3软件进行Meta分析。结果共纳入17篇病例对照研究,共1 521例患者,其中腹腔镜组766例,开腹组755例。Meta分析结果显示:腹腔镜组的手术时间、术中出血量、结石残留率及并发症发生率均低于开腹组,差异具有统计学意义(P=0.000)。结论腹腔镜联合胆道镜钬激光在治疗胆管结石的疗效和安全性方面均优于开腹术,值得进一步在临床推广,但仍需大样本高质量的病例对照研究进行验证。
【Objective】To systematically evaluate the efficacy of laparoscopic cholangioscopy combined with holmium laser therapy for cholangiolithiasis by using a meta-analysis.【Methods】The randomized controlled studies on the comparison of laparoscopic cholangioscopy combined with holmium laser therapy and open surgery for cholangiolithiasis in recent five years(2013-2018)published in Chinese National Knowledge Infrastructure(CNKI),Wanfang database,VIP database,Web of science and PubMed database were searched.After screening for inclusion and data extraction,a Meta-analysis was conducted with Review Manager 5.3 software.【Results】A total of 17 case-controlled studies were included,containing 1521 cases(766 cases in laparoscope group and 755 cases in open group).The operation time,intraoperative blood loss,residual stone rate and postoperative complications rate in laparoscope group were lower than those in the open group,and the difference was statistically significant(P=0.000).【Conclusion】The efficacy and safety in the laparoscopic cholangioscopy combined with holmium laser therapy for cholangiolithiasis were significantly better than the open surgery,which was worthy of clinical promotion.However,further larger and higher quality studies were expected to verify the finding.
作者
仝麟龙
张俊杰
TONG Linlong;ZHANG Junjie(Department of General Surgery,Zhengzhou People's Hospital,Zhengzhou,Henan 450000,China)
出处
《中国医学工程》
2019年第1期10-14,共5页
China Medical Engineering
关键词
腹腔镜
胆道镜
钬激光
残石率
并发症
laparoscope
choledochoscope
holmium laser
residual stone rate
complication
