摘要
本文报道使用不同浓度中药健脾益气合剂及VitE分别喂养老龄鼠,测定其血液、肝脏、脑组织脂质过氧化物(LPO)含量,并与空白对照组比较,结果显示:中药组老龄鼠血液、肝脏LPO含量明显低于空白对照组,差异有显著性意义(P<0.01),VitE组与空白对照组比较,差异无意义(P>0.05),脑组织LPO含量各组比较,差异无意义(P>O.05),提示使用中药健脾益气合剂治疗以气虚为临床特征的AMD一病,可提高体内自由基清除能力,达到保护细胞的正常生理功能。
Fifty elder rats were divided into five groups. Three groups were fed by Han Pi Yi Qi mixture (a herbal mixture for benefiting-qi and invigorating spleen) in different concentration, one group was fed by Vitamine E, and the rest was the control group. LPO contents in the blood, liver, and brain of the experimental groups were measured and compared with those of the control group. The results showed that the LPO contents in the blood and liver of rats in the Jian Pi Yi Qi mixture group were less than those in the control group (p<0.01). However, the difference was not significant when the Vitamine E group was compared with the control group. But the difference of LPO contents in the brain was not significant in individual groups (p>0.05) It is suggested that Jian Pi Yi Qi mixture could enhance the scavenging ability of free radical and could be a remedy for aging macular degeneration with qideficiency.
关键词
健脾益气合剂
鼠
抗老化作用
分子生物学
自由基
QI-REINFORCING AGENTS/pharm. LIPID PEROXIDES/anal. BRAIN CHEMISTRY/drug eff. LIVER/chemistry MACULAR EDEMA, CYSTOID/TCM ther. SPLEEN QI DEFICIENCY/TCM ther. QI-REINFORCING AGENTS/ther. use
