摘要
目的 研究应用异丙酚作镇静麻醉用于结肠镜检查治疗术中的安全性、有效性和不良反应。方法 麻醉组 3 16例给予异丙酚静脉注射麻醉镇静结肠镜检查治疗 ,对照组 14 2例常规进行结肠镜诊疗 ,比较两组结肠镜操作时间及患者反应 ,观察麻醉组清醒时间及检查前、中、后血压、心率和血氧饱和度变化。结果 麻醉组 3 16例中 3 15例顺利完成检查 ,成功率 99.7% ,对照组 14 2例 ,13 6例完成检查 ,成功率为 95 8% ,两组比较有显著性差异 (P <0 .0 5)。麻醉组结肠镜到达回盲部的平均时间为 7 3± 1.4min ,对照为 12 .5± 1.6min(P <0 .0 5)。麻醉组患者清醒时间为 1min～ 8min。操作过程中均见一过性血压和心率下降 ,但检查结束后又恢复到原来水平。对照组操作过程中均有不同程度的血压升高 ,心率加快 ;两组操作前、中、后的SpO2 值无显著性差异 (P >0 .0 5)。结论 应用异丙酚作镇静麻醉于结肠镜检查治疗术安全有效 ,操作时间缩短 。
ObjectiveTo study the safety and efficacy a s well as the adverse reactions of sedation and anesthesia under colonoscopy with intr aveneous propofol.Methods316 patients of anesthesia group were performed colonos copy with intraveneous propofol,and 142 patients of control group were performed with traditional methods.Time of operation,patients feeling and discomfort in a nesthesia group were compared with that in control group.The changes of blood pr essure,heart rate and blood oxygen saturation and time of patients recover consc iousness were recorded and analysed during colonoscopy.Results315 patients were finished colonoscopy successfully in 31 6 patients of anesthesia group,and 136 patients were finished colonoscopy in 142 patients of control group,the success rate was 99.7% and 95.8%,respectively(P <0.05).The time of that colonoscope reached ileocecal valve was(7.3±1.4) min in anesthesia group and (12.5±1.6) min in control gruop (P<0.05).Patients recover consciousness in 1 min～8 min.Both the blood pressure and heart rate we r e decreased in anesthesia group during colonoscopic procedure and recovered afte r colonoscopy.On the other hand,Both the blood pressure and heart rate we re incr eased in control group.There was no significant difference in SpO 2 during the procedure of examination in two groups.ConclusionIt was safe and effective to perform colonoscope with intraveneous propofol,and the adverse reactions was much lower than that of trad itional methods.
出处
《胃肠病学和肝病学杂志》
CAS
2003年第6期566-568,共3页
Chinese Journal of Gastroenterology and Hepatology
