摘要
本文采用胶乳凝集半定量方法对67名健康成人献血员、30例2～4日正常新生儿、33例肝病患者(7例肝癌、20例肝硬化、6例慢性肝炎)及服用华法令者21例、头孢菌素类药物者10例血浆中异常凝血酶原的存在状况进行了检测并对异常凝血酶原的生成与体内维生素K状况间的关系进行了探讨。认为异常凝血酶原的检测有可能发展为观测体内维生素K状况,早期诊断体内维生素K利用障碍或缺乏所致出血的一种新手段。
Plasma PIVKA-Ⅱ levels were evaluated by half-quantity latex method in 67 heal-thy donors, 30 cases of 2～4 day newborn. 7 cases of hepatocellular carcinoma, 20 ca-ses of liver cirrhosis, 6 cases of chronic hepatitis and 21 patients treated withWarfarin and 10 patients treated with cephalosporins. The relationship betweenPIVKA-Ⅱ and vitamin K was studied. Plasma PIVKA-Ⅱ levels might be a new wayto evaltate intracorporal vitamin K level and for the early diagnosis of bleeding dueto vitamin K deficiency or metabolic disorders.
出处
《天津医药》
CAS
1992年第10期600-602,共3页
Tianjin Medical Journal
