摘要
目的 :探讨脑脊液中 β-葡萄糖醛酸酶 ( β- G)活性测定对脑肿瘤诊断的临床意义。方法 :建立酶联免疫吸附试验 ( ELISA)技术测定脑肿瘤及非肿瘤脑病患者脑脊液中 β- G活性。结果 :恶性脑肿瘤患者脑脊液 β- G活性明显高于良性脑肿瘤、非肿瘤脑病患者及其他对照组 ( P<0 .0 1 ) ;恶性脑肿瘤患者术后脑脊液 β- G活性呈下降趋势。结论 :检测脑脊液中β- G活性 。
Objective:To study the clinical significance of the detection of activity of β-G in CSF (cerebrospinal fluid) of patients with cerebral tumor. Methods:Enzyme-linked immunosorbent assay(ELISA) was set up to measure the activity of β-G in CSF of patients with cerebral tumor or and without cerebral tumor. Results: The activity of β-glucuronidase in patients with cerebral malignancy were obviously higher than that in patients with cerebral benign tumor?without cerebral tumor and control group(P<0.01); the activity of β-glucuronidase in CSF of patients with cerebral malignancy was showed descending tendency after operation. Conclusions: To detect the activity of β-glucuronidase in CSF is of reference to diagnosis of cerebral malignancy and determine of the course of the cerebral malignancy.
出处
《陕西医学杂志》
CAS
北大核心
2004年第1期70-72,共3页
Shaanxi Medical Journal
基金
辽宁科技攻关计划基金资助项目 (项目号 :982 2 5 0 0 3 )
关键词
ELISA法
测定
脑脊液
Β-葡萄糖醛酸酶
脑肿瘤
诊断
Cerebral tumor/enzymology β-glucuronidase/enzymology Enzyme-linked immunosorbent assay(ELISA)
