摘要
目的 了解支气管动脉内应用立止血治疗肺结核大咯血的效果。方法 34例浸润型肺结核和慢性纤维空洞型肺结核大咯血病人,咯血量≥300 ml/d者26例,≥600 ml/d者8例;靶血管内单纯使用立止血者13例,(立止血1～3KU/次);局部注射立止血+明胶海绵颗粒栓塞者21例(靶血管内应用立止血后,再用1～2 mm明胶海绵颗粒进行栓塞)。结果 局部应用立止血或加栓塞治疗大咯血的34例病人,治疗1次的32例、2次的1例、3次的1例。单纯立止血治疗13例,12例有效,有效率92.3％;双重治疗组21例,20例有效,有效率为95％。两组无显著性差异(P>0.05)。结论 靶血管内应用立止血或加栓塞治疗肺结核大咯血是一种安全有效的方法,无明显副作用。在无法行靶血管栓塞的情况下,局部注射立止血也是有效和可行的方法。
Objective To investigate the effect of bronchial artery infusion with Reptilase or plus additional target artery embolization in treatment of massive hemoptysis in patients with pulmonary tuberculosis. Methods Among 34 patients with massive hemoptysis (≥600 ml/24hours) resultant from pulmonary tuberculosis, 21 cases (group 1) received by bronchial artery infusion with Reptilase (1-3KU) plus target artery embolization with gelfoam sponge. In the rest 13 cases (group 2) a simple bronchial artery infusion with Reptilase (1-3KU) was performed because the bleeding target arteries were inaccessible. Results In total 32 cases out of 34 (94. 1% ) the hemoptysis ceased after the intervention, while in 1 case in each group respectively needed further surgery. Among the cured 34 cases, single treatment was done in 32 cases, twice interventions were performed in 1 case and triple intraluminal therapies were done in 1 case. There is no significant difference between the efficiency of the treatment applied in group 1 and group 2 (P > 0.05). Conclusion Bronchial artery infusion with Reptilase or plus additional target artery embolization is effective and safe method in the management of massive hemoptysis in patients with pulmonary tuberculosis. When the target the bleed artery is inaccessible, local intraluminal infusion with Reptilase (1-3KU) is an acceptable option.
出处
《影像诊断与介入放射学》
2003年第4期217-220,共4页
Diagnostic Imaging & Interventional Radiology
