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地佐辛在预防全麻拔管期心血管反应中的应用体会 被引量:3

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摘要 选取2013年4月~2014年4月我院80例行全麻手术患者.随机分为对照组和观察组各40例.对照组在拔管前2min注射5ml生理盐水,观察组在拔管前2min注射0.1mg/kg地佐辛,比较两组在预防全麻拔管期心血管反应中的作用.结果两组患者麻醉前心率差异不显著(P>0.05);观察组麻醉时T1心率指标为110.9±9.8次/min、T2心率为113.8±9.1次/min、T3心率为110.7±7.8次/min、T4心率为112.8±8.3次/min,均低于对照组心率(P<0.05);观察组麻醉时T1 MAP为80.5±5.5,T2MAP为79.8±5.0mmHg、T3MAP为78.2±5.6mmHg、T4MAP为80.2±5.5mmHg,和对照组相比具有统计学意义(P<0.05);两组麻醉前后TSP02和Pmax差异不显著(P>0.05);观察组1例出现呛咳、2例呕吐返流、1例喉痉挛,不良反应率为10.5%,低于对照组26.3% (P<0.05).全麻拔管期对患者静脉注射地佐辛效果理想,能够降低围手术期心血管反应,具有良好的镇痛作用,且不会延长复苏时间,不会增加并发症发生率,值得推广使用.
作者 黄翠星
出处 《现代诊断与治疗》 CAS 2014年第19期4395-4397,共3页 Modern Diagnosis and Treatment
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