摘要
目的:探讨二甲双胍对2型糖尿病合并结直肠癌患者预后的影响。方法:收治2型糖尿病合并结直肠癌患者100例,随机分为对照组与观察组,每组50例。对照组采用常规降糖药物治疗,观察组采用二甲双胍治疗,比较两组治疗效果及对预后的影响。结果:观察组死亡6例,死亡率12.00%;对照组死亡26例,死亡率52.00%,两组对比差异有统计学意义(P<0.05)。观察组12例出现肿瘤转移,对照组17例出现肿瘤转移,两组对比差异有统计学意义(P<0.05)。结论:对于2型糖尿病合并结直肠癌患者采用二甲双胍治疗有效降低了血糖水平,对肿瘤预后有较佳影响。
Objective:To explore the effect of metformin on the prognosis of patients with type 2 diabetes combined colorectal cancer.Methods:100 cases of patients with type 2 diabetes combined colorectal cancer were randomly divided into the control group and the observation group,with 50 cases in each group.The control group were treated with conventional hypoglycemic drug, and the observation group were treated with metformin.The treatment effect and its influence on prognosis of the two groups were compared.Results:6 cases died in the observation group and the mortality rate was 12.00%;26 cases died in the control group and the mortality rate was 52.00% ;there was statistically significant difference between the two groups(P<0.05).12 cases in the observation group had tumor metastasis and 17 cases in the control group had tumor metastasis;there was statistically significant difference between the two groups(P<0.05).Conclusion:Metformin in the treatment of patients with type 2 diabetes combined colorectal cancer reduced the blood sugar level effectively and had better effect on the prognosis of tumor.
出处
《中国社区医师》
2015年第21期74-74,76,共2页
Chinese Community Doctors
关键词
二甲双胍
2型糖尿病
直肠癌
预后
Metformin
Type 2 diabetes
Rectal cancer
Prognosis
