摘要
目的:分析川芎嗪对胸部肿瘤放射治疗后肺损伤的干预作用。方法:收治胸部肿瘤放射治疗患者80例,随机分为对照组和观察组。对照组给予常规胸部肿瘤放射治疗,观察组在对照组的基础上服用川芎嗪,测定放射治疗前后的血浆TGF-β1。结果:放射治疗后,观察组血浆TGF-β1(5.81±2.89)ng/m L明显低于对照组的(11.7±5.49)ng/m L(P<0.05)。结论:川芎嗪能够抑制放射治疗后血浆TGF-β1的过度表达,能够有效地抑制和干预患者的肺损伤,提高患者的生活质量,减轻不良反应。
Objective:To analyze the intervention effect of ligustrazine on the lung injury after thoracic tumor radiotherapy.Methods:80 patients with thoracic tumor radiotherapy were selected.They were randomly divided into the observation group and the control group.The control group was given routine thoracic tumor radiotherapy.The observation group was given ligustrazine on the basis of the control group.The plasma TGF-beta 1 was measured before and after radiotherapy.Results:After radiotherapy,the plasma TGF-beta 1(5.81±2.89)ng/m L of the observation group was significantly lower than(11.7±5.49)ng/m L of the control group(P<0.05).Conclusion:Using ligustrazine can inhibit the over expression of plasma TGF-beta 1 after radiotherapy.It can effectively inhibit and intervene the lung injury of patients,improve the life quality of patients,and reduce the adverse reaction.
出处
《中国社区医师》
2015年第19期87-88,共2页
Chinese Community Doctors
关键词
川芎嗪
胸部肿瘤
肺损伤
Ligustrazine
Thoracic tumor
Lung injury
