摘要
目的:观察评价蛇毒血凝酶治疗肺结核大咯血的临床疗效与安全性。方法:收治肺结核大咯血患者24例,回顾性分析其临床资料,选择垂体后叶素+硝酸甘油止血的12例纳入对照组,选择蛇毒血凝酶肌注的12例纳入观察组,对比相关指标。结果:观察组起效时间(5±1)min,咯血消失时间(2±2)h,咯血量(310±207)m L,低于对照组的(14±9)min、(28±15)h、(582±174)m L;观察组住院期间复发率0、不良反应发生率0,低于对照组的41.67%、50.00%,差异均有统计学意义(P<0.05)。结论:以蛇毒血凝酶治疗肺结核大咯血,止血速度快、1次成功率高、复发率低、不良反应少、操作简单,是一种理想的肺结核大咯血止血剂,但使用时需具有一定预见性。
Objective:To observe and evaluate the clinical effect and security of hemocoagulase in the treatment of pulmonary tuberculosis hemoptysis.Methods:24 patients with pulmonary tuberculosis hemoptysis were selected.The clinical data were retrospectively analyzed.12 cases of hypophysin + nitroglycerin bleeding were selected as the control group.12 cases of hemocoagulase intramuscular were selected as the observation group.The related indicators were compared.Results:The onset time of the observation group (5±1)minutes,the haemoptysis disappeared time (2±2)hours,the amount of hemoptysis (310±207) mL were lower than (14±9)minutes,(28±15)hours and (582±174)mL of the control group.The recurrence rate 0.00% and the adverse reaction incidence rate 0.00% of the observation group during hospitalization were lower than 41.67% and 50.00% of the control group.The differences were statistically significant(P<0.05).Conclusion:The hemocoagulase in the treatment of pulmonary tuberculosis hemoptysis has quickly hemostatic speed and high first time success rate,low recurrence rate and less adverse reaction.The operation is simple.It is ideal pulmonary tuberculosis hemoptysis hemostatic agent,but its use needs to have a certain predictability.
出处
《中国社区医师》
2015年第3期24-24,26,共2页
Chinese Community Doctors
关键词
肺结核
大咯血
蛇毒血凝酶
临床效果
不良反应
Pulmonary tuberculosis
Hemoptysis
Hemocoagulase
Clinical effect
Adverse reaction
