摘要
目的:探讨经肝动脉加温化疗肝恶性肿瘤的价值。方法:肝恶性肿瘤50例,经肝动脉加温化疗150次。灌注温度43~45℃,流速20~50 m L/min,总量600~1 000 m L,时间30~60 min。化疗药物(5-Fu 0.75~1.0 g、MMC12~20 mg、DDP 60~80 mg)3药联用。结果:经>2次治疗,随访6~48个月,资料完整50例。近期有效率88.7%(CR 4例,PR 41例,NC 5例),术中患者均有不同程度的心窝部灼热感、全身发热及出汗等,术后不良反应与常温法相近。结论:通过导管将热疗与化疗相结合的方法治疗肝恶性肿瘤疗效肯定,且没有严重不良反应。
Objective:To investigate the value of hepatic artery plus hyperthermic chemotherapy on hepatic malignant tumor.Methods:50 cases of hepatic malignant tumor were treated with chemotherapy of hepatic artery heating for 150 time.Pouring temperature of 43 to 45 ℃,the velocity of 20~50 m L/min,a total of 600~1 000 m L,30~60 min time.Chemotherapy drugs(5-Fu0.75~1.0 g,MMC 12~20 mg,DDP 60~80 mg) with 3 drugs combined.Results:After 2 or more treatment,and all of the 50 cases were followed up for 6~48 months with complete data.The short-term effective rate was 88.7%(CR 4 cases,PR 41 cases,NC 5cases).During the operation,the patients had different degree of intraoperative heart burning,fever and sweating,the adverse reaction of postoperative as same with normal temperature technique.Conclusion:The methods of hyperthermia combined with chemotherapy through the catheter have certain curative effect in the treatment of liver malignant tumor,and no serious adverse reaction.
出处
《中国社区医师》
2015年第2期23-24,共2页
Chinese Community Doctors
关键词
肝肿瘤
热疗
化学疗法
临床分析
Liver neoplasms
Hyperthermia
Chemical therapy
Clinical analysis
