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乌司他丁治疗脓毒症疗效的系统评价

Systematic evaluation of the therapeutic effect of ulinastatin in the treatment of sepsis.
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摘要 目的:探讨乌司他丁治疗脓毒症的疗效。方法:2012年7月-2013年7月收治脓毒症患者80例,随机分为对照组和试验组,对照组给予常规治疗,试验组在对照组的基础上联合乌司他丁治疗。比较两组患者的临床疗效。结果:治疗后,试验组的APACHEⅡ评分、MarshaⅡ评分改善情况明显优于对照组,差异有统计学意义(P<0.05)。治疗后,试验组的IL-6、TNF-α、Ny-pro BNP水平明显比对照组低,差异有统计学意义(P<0.05)。结论:乌司他丁治疗脓毒症患者疗效理想,安全可靠,值得普及和应用。 Objective:To investigate the effect of ulinastatin in the treatment of sepsis.Methods: 80 patients with sepsis were selected from July 2012 to July 2013.They were randomly divided into the control group and the experimental group.The control group were given conventional therapy.The experimental group combined with ulinastatin on the basis of the control group.We compared the clinical efficacy of two groups.Results:After the treatment,the APACHE Ⅱ score,and Marsha Ⅱ score of the experimental group were significantly higher than those of the control group,and the difference was statistically significant(P<0.05).After the treatment,the IL-6,TNF-alpha,Ny-pro BNP levels of the experimental group were significantly lower than those of the control group,and the difference was statistically significant(P<0.05).Conclusion:The effect of ulinastatin in treating patients with sepsis are safe and reliable,and it is worthy to be popularized and applied.
出处 《中国社区医师》 2015年第2期20-21,共2页 Chinese Community Doctors
关键词 乌司他丁 脓毒症 系统评价 Ulinastatin Sepsis System evaluation
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